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Glycopyrrolate - Indications, Dosage, Side Effects and Precautions

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Glycopyrrolate Medication Information

Learn everything you need to know about Glycopyrrolate-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Glycopyrrolate brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Glycopyrrolate
Pronunciation : glye-koe-PYE-roe-late

Brand Names or Trade Names of Glycopyrrolate

India :

International :


Robinul, Cuvposa

Other Name(s) of Glycopyrrolate

Glycopyrronium Bromide

Why is Glycopyrrolate Prescribed? (Indications)

This medication is a muscarinic anticholinergic agent, prescribed for peptic ulcer in combination with other medicines and also used in anesthesia as preoperative medication. It reduces acid and saliva secretions.

When should Glycopyrrolate not be taken? (Contraindications)

Contraindicated in patients with glaucoma, trouble urinating (eg, bladder neck obstruction), certain stomach or bowel problems (eg, stomach or bowel blockage, bowel muscle problems, severe ulcerative colitis, toxic megacolon), certain esophagus problems (eg, achalasia, reflux), or myasthenia gravis, and hypersensitivity.

What is the dosage of Glycopyrrolate?

IV/IM: Peptic Ulcer: 100mcg/kg, 3 to 4 times/day. In anesthetic: 4mcg/kg over 1hr.

How should Glycopyrrolate be taken?

It comes as a solution for injection, administered by a healthcare provider.

What are the warnings and precautions for Glycopyrrolate?

•Caution should be exercised in patients with history of pregnancy, breastfeeding, heart disease, increased level of thyroid hormone, liver or kidney impairment, enlarged prostate, diarrhea, fever, children and elderly people.

It may cause ileus (abruption of gastrointestinal motor activity) or megacolon in patients with ulcerative colitis.

Patient may develop dizziness or drowsiness; avoid driving a car or operating machinery while taking this medication.

Avoid alcoholic beverages.

Use appropriate solution if you are wearing contact lenses while taking this medication.

What are the side effects of Glycopyrrolate?

Most common- Dry mouth, difficulty in urinating, headaches, diarrhea and constipation.
Central Nervous System- Drowsiness, dizziness, problem in sleeping, headache, confusion and nervousness.
Heart- Irregular heart beat, cardiac arrest, high/low blood pressure and prolonged QT interval.
Skin- Itching, rash, redness and dry skin.
Respiratory- Respiratory arrest.
Gastrointestinal- Nausea; vomiting and loss of taste.
Hypersensitivity- Severe allergic reactions including anaphylactic/anaphylactoid reactions and hives.
Genitourinary- Impotence.
Miscellaneous- Fever and decreased sweating.
Potentially Fatal - Severe anaphylaxis.

What are the other precautions for Glycopyrrolate?

Avoid hot environments.

What are the storage conditions for Glycopyrrolate?

Injection: Store at 20-25°C. Store it at room temperature and in airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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