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Guanethidine Monosulfate - Indications, Dosage, Side Effects and Precautions

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Guanethidine Monosulfate Medication Information

Discover comprehensive details about Guanethidine Monosulfate, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Guanethidine Monosulfate brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Guanethidine Monosulfate
Pronunciation : gwahn-ETH-ih-deen MAH-no-SULL-fate
ICD Code : Y52.5 Therapeutic Classification : Anti- Adrenergic Blockers - Peripherally Acting

Brand Names or Trade Names of Guanethidine Monosulfate

International :


Ismelin

Why is Guanethidine Monosulfate Prescribed? (Indications)

This medication is an antihypertensive, prescribed for severe hypertension either alone or with other medications.

When should Guanethidine Monosulfate not be taken? (Contraindications)

Contraindicated in patients with heart failure, pheochromocytoma (neuroendocrine tumor), who are taking monoamine oxidase (MAO) inhibitors and hypersensitivity.

What is the dosage of Guanethidine Monosulfate?

Adults- The recommended initial dose 10 or 12.5 milligrams (mg) once a day.
Children- PO- 0.2 mg/kg/24 h (6 mg/m 2 /24 h ) as single oral dose initially.

How should Guanethidine Monosulfate be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Guanethidine Monosulfate?

• Caution should be exercised in patients with asthma, heart disease, fever, low blood pressure, ulcer, kidney or liver impairment, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness or blurred vision, lie down or get up slowly from bed.

• Avoid alcohol consumption while taking this medication.

• Avoid abrupt withdrawal.

• Monitor blood pressure, heart and liver function regularly while taking this medication.

What are the side effects of Guanethidine Monosulfate?

Gastrointestinal - Diarrhea, vomiting, nausea, increased bowel movements, dry mouth, and parotid tenderness.
Heart - Chest pain, slow heart rate, fluid retention, and heart failure.
Respiratory - Difficulty in breathing, asthma and nasal congestion.
Central Nervous System - Fainting, dizziness, blurred vision, tremor, ptosis of the lids, depression, tingling, weakness, lassitude, and fatigue.
Musculoskeletal - Muscle pain.
Genitourinary - Rise in BUN, urinary incontinence, inhibition of ejaculation, nighttime urination.
Metabolic - Weight gain.
Skin - Skin inflammation, and scalp hair loss.

What are the other precautions for Guanethidine Monosulfate?

Avoid excess dosage.

What are the storage conditions for Guanethidine Monosulfate?

Store it in airtight container at room temperature.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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