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Ibritumomab Tiuxetan - Indications, Dosage, Side Effects and Precautions

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Ibritumomab Tiuxetan Medication Information

Get detailed information on Ibritumomab Tiuxetan, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Ibritumomab Tiuxetan provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Ibritumomab Tiuxetan
Pronunciation : EYE-bri-TOOM-oh-mab tye-UX-e-tan/IN-dee-um
ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Ibritumomab Tiuxetan

International :


Zevalin Kit-Indium-111

Why is Ibritumomab Tiuxetan Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for non-Hodgkin's lymphoma with other medications. It works by killing certain blood and cancer cells from body immune system.

When should Ibritumomab Tiuxetan not be taken? (Contraindications)

Contraindicated in patients with bone marrow depression and hypersensitivity.

What is the dosage of Ibritumomab Tiuxetan?

Adults- IV- Step 1: Infuse rituximab 250 mg/m 2 at a rate of 50 mg/h, escalate the dose up to 400mg/hr. After this administer indium-111 (In-111) ibritumomab tiuxetan 5 mCi (1.6 mg total antibody dose) administered as a 10-min IV push.
Step 2: Continue this procedure for 7 to 9 days.

How should Ibritumomab Tiuxetan be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Ibritumomab Tiuxetan?

• Caution should be exercised in patients with history of blood disorders, decrease in complete blood cell counts due to bone marrow depression, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections.

• Patient may develop with increased the risk of certain blood cancers; consult with your doctor before taking this medication.

• Avoid live vaccination during the treatment period.

• Monitor complete blood counts regularly while taking this medication.

What are the side effects of Ibritumomab Tiuxetan?

Most Common - Reduction in the number of blood cells, fatigue, abdominal pain, nausea, cold, weakness, diarrhea, cough and fever.
Body as a Whole - Influenza-like illness.
Musculoskeletal - Muscle pain and loss of appetite.
Respiratory - Cough, throat pain, upper respiratory tract infection and nosebleed.
Central Nervous System - Dizziness.
Heart - High blood pressure.
Skin - Night sweats, blister, itching and rash.
Genitourinary - Urinary tract infection.

What are the other precautions for Ibritumomab Tiuxetan?

Avoid excess dosage.

What are the storage conditions for Ibritumomab Tiuxetan?

Store it in refrigerator (2-8°C). Do not freeze.

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