Medindia LOGIN REGISTER
Medindia

Imipramine - Indications, Dosage, Side Effects and Precautions

Advertisement

Imipramine Medication Information

Get detailed information on Imipramine, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Imipramine provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Imipramine
Pronunciation : im ip' ra meen
ICD Code : Y49.0 Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Imipramine

India :

International :


Tofranil

Why is Imipramine Prescribed? (Indications)

This medication is an antidepressant, prescribed for depression. It is also used to treat bedwetting in children. It increases the amount of certain natural substances in the brain.

When should Imipramine not be taken? (Contraindications)

Contraindicated in patients with recovery period after a heart attack, who are taking MAOIs, linezolid or intravenous methylene blue and hypersensitivity.

What is the dosage of Imipramine?

Adult: PO- Initial dose: 100 mg per day given in 3 to 4 divided doses.
Pediatric Dose for Primary Nocturnal Enuresis: Initial dose: 25 mg per day orally 1 hour before bedtime.

How should Imipramine be taken?

It comes as a tablet and capsule to take by mouth, with or without food.

What are the warnings and precautions for Imipramine?

• Caution should be exercised in patients with history of increased eye pressure, prostate enlargement, difficulty in urinating, seizures, overactive thyroid, liver, kidney or heart disease, any allergy, who are taking other medications, during pregnancy and breast feeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption and smoking while taking this medication.

• Avoid exposure to sunlight; otherwise it may cause skin sensitivity.

• Patient may develop Serotonin Syndrome with the following symptoms: increased heart rate, shivering, sweating, dilated pupils.

What are the side effects of Imipramine?

Heart - Low/high blood pressure, fast heart rate, palpitations, heart attack, abnormal heart rhythm, heart block, ECG changes, heart failure and stroke.
Psychiatric - Confusion, hallucinations, disorientation, anxiety, restlessness, agitation, sleeplessness, abnormal dreams and irritable mood.
Central Nervous System - Numbness, tingling, incoordination, tremors, seizures, alterations in EEG patterns and ringing in the ear.
Eye - Blurred vision, visual disturbances and dilatation of pupil.
Allergic Reactions - Skin rash, hives, itching, photosensitization, swelling in the face and tongue and fever.
Blood - Bone marrow depression.
Gastrointestinal - Nausea, vomiting, dry mouth, loss of appetite, constipation, stomach upset, diarrhea, intestinal obstruction, mouth ulcer, abdominal cramps and black tongue.
Genitourinary - Breast enlargement in the male, spontaneous milk secretion in the female, increased or decreased sexual drive, impotence, testicular swelling, elevation or depression of blood sugar levels, urinary retention and dilation of the urinary tract.
Other - Jaundice and hair loss.

What are the other precautions for Imipramine?

Avoid excess dosage.

What are the storage conditions for Imipramine?

Store it at room temperature (20° to 25°C), and in an airtight container. Keep away from children.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Advertisement
Recommended Reading