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Laronidase - Indications, Dosage, Side Effects and Precautions

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Information about Laronidase

Generic Name : Laronidase
Up-to-date prescription details regarding Laronidase are provided here.

Pronunciation : lar-ON-i-dase

Learn the correct pronunciation of the Laronidase, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Therapeutic Classification : Endocrine and Metabolic Agents

Trade Names/Brand Names of Laronidase

International :


Aldurazyme

Why is Laronidase Prescribed? (Indications)

This medication is a glycoprotein, prescribed for patients with Hurler and Hurler-Scheie forms of mucopolysaccharidosis I (MPS I- series of inherited metabolic disorders). It provides the enzyme alpha-L-iduronidase to the body.

When should Laronidase not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Laronidase?

The recommended dosage regimen is 0.58 mg/kg of body weight administered once weekly as an intravenous infusion.

How should Laronidase be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Laronidase?

• Caution should be exercised in patients with history of lung or breathing problems, any allergy, who are taking other medications, children less than 5 years old, during pregnancy and breastfeeding.

• Patients may develop with severe allergic reactions; if it so consult with your doctor immediately.

What are the side effects of Laronidase?

Most Common- Upper respiratory tract infections, rash, injection site reaction, fever and headache.
Skin- Hives and itching.
Respiratory- Cough, asthma and difficulty in breathing.
Body as a Whole- Chest pain.
Nervous System- Overactive reflexes and tingling.
Liver- Excess bilirubin in blood.
Urinary System- Facial swelling.
Heart- Low blood pressure.
Eye- Eye disorder.
Miscellaneous- Injection site pain, swelling and decrease in platelets.

What are the other precautions for Laronidase?

Avoid excess dosage.

What are the storage conditions for Laronidase?

Store it in refrigerator (2°C to 8°C). The diluted solution should be used immediately.
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