Information about Latanoprostene Bunod Ophthalmic

Generic Name : Latanoprostene Bunod Ophthalmic
Up-to-date prescription details regarding Latanoprostene Bunod Ophthalmic are provided here.

Pronunciation : la-TAN-oh-PROS-teen BUE-nod off-THAL-mik

Learn the correct pronunciation of the Latanoprostene Bunod Ophthalmic, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Therapeutic Classification : Antiglaucoma Agents

Trade Names/Brand Names of Latanoprostene Bunod Ophthalmic

India :

Vyzulta

Overview of Latanoprostene Bunod Ophthalmic

• The US FDA approved Latanoprostene bunod 0.024% ophthalmic solution in November 2017 for treating patients with ocular hypertension or open-angle glaucoma.

Why is Latanoprostene Bunod Ophthalmic Prescribed? (Indications)

Latanoprostene bunod ophthalmic belongs to a class of prostaglandin analogs which is prescribed to treat patients suffering from open-angle glaucoma or ocular hypertension.
It works by reducing pressure inside the eye by increasing the drainage of the fluids from the eye.

When should Latanoprostene Bunod Ophthalmic not be taken? (Contraindications)

Latanoprostene bunod ophthalmic should not be used in patients with-

• Allergy to latanoprostene bunod ophthalmic
• Children below 16 years of age
• Inflammation of the eye (Iritis or uveitis)
• Pregnancy

What is the dosage of Latanoprostene Bunod Ophthalmic?

• The recommended dose of latanoprostene bunod ophthalmic is one drop of 0.24 mg/ml applied to the affected eye once daily in the evening.
• Do not use more than once as frequent administration leads to reduced therapeutic activity.

How should Latanoprostene Bunod Ophthalmic be taken?

• Latanoprostene bunod ophthalmic comes as a liquid which has to be instilled into the conjunctival sac of the affected eye daily in the evening.
• If latanoprostene bunod ophthalmic is prescribed with other eye drops, maintain a time gap of around 5 minutes between each administration.

What are the warnings and precautions for Latanoprostene Bunod Ophthalmic?

• Patients should be advised about the chances of increased pigmentation of the iris and the eyelids, which may last even after the discontinuation of the treatment.

• Changes in the thickness, length, and the number of hairs in the eyelashes may be noticed in patients on latanoprostene bunod therapy which is reversible after stopping the treatment.

• Before initiating the treatment, it is necessary to evaluate the patient for intraocular inflammation such as uveitis or iritis as latanoprostene bunod therapy may worsen the condition.

• Caution is required while using in patients with known risk factors for macular edema, including aphakic or in pseudophakic patients with a torn posterior lens capsule. Aphakia refers to the absence of the eye lens, while pseudophakia refers to a condition where the natural lens has been replaced by an artificial lens. Macular edema refers to the swelling of the macula, the part on the inner light-sensitive layer of the eye responsible for sharp vision.

What are the side effects of Latanoprostene Bunod Ophthalmic?

• Pain and irritation of the eye
• Conjunctival hyperemia or redness of the eye
• Puffy eyelids
• Pigmentation of the iris of the eye and the eyelids
• Changes in the eyelashes
• Blurred vision
• Macular edema
• Infection of the cornea (bacterial keratitis)
• Worsening of eye inflammation

What are the other precautions for Latanoprostene Bunod Ophthalmic?

• Contact lens users are advised to remove the lenses before the application of latanoprostene bunod solution to avoid damage to the lens. It can be reinserted 15 minutes after administering the drops.
• Patients should be advised not to touch the tip of the container to avoid the risk of contamination as it may result in severe eye infection leading to eye damage or loss of vision.
• Stop using latanoprostene bunod and report to the emergency center if itching, swelling, redness of the eye, eye drainage or sudden changes in vision occur.

What are the Drug Interactions of Latanoprostene Bunod Ophthalmic?

• Not known.

What are the storage conditions for Latanoprostene Bunod Ophthalmic?

• Store the unopened container in a refrigerator at 2°C to 8°C.
• After opening store the container either at a cold storage or at room temperature for up to 8 weeks and should be discarded thereafter.
• Do not freeze.
• Protect from excess heat and moisture.