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Lepirudin - Indications, Dosage, Side Effects and Precautions

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Lepirudin Medication Information

Learn everything you need to know about Lepirudin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Lepirudin brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Lepirudin
Pronunciation : le-PEER-u-din
ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Brand Names or Trade Names of Lepirudin

International :


Refludan

Why is Lepirudin Prescribed? (Indications)

This medication is an anticoagulant, prescribed for heparin-induced thrombocytopenia (HIT). It blocks thrombin activity that helps to prevent the formation of blood clots.

When should Lepirudin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Lepirudin?

Adult: IV- 0.4 mg/kg body weight (up to 110kg) slowly intravenously (eg, over 15 to 20seconds) as a bolus dose.
Followed by 0.15 mg/kg body weight (up to 110kg)/hour as a continuous intravenous infusion for 2 to 10 days or longer if clinically needed.

How should Lepirudin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Lepirudin?

• Caution should be exercised in patients with history of heart infection, high blood pressure, stomach ulcers, liver or kidney problems, head injury, stroke, any allergy, bleeding problems, stomach/intestinal problems, elderly, children, during pregnancy and breastfeeding.

• Monitor blood counts, blood pressure while taking this medication.

What are the side effects of Lepirudin?

Heart- Heart failure.
Skin- Bleeding in injection site, wounds and allergic skin reactions.
Eye and ENT- Nosebleed.
Gastrointestinal- Gastrointestinal and rectal bleeding.
Genitourinary- Abnormal kidney function, blood in urine and vaginal bleeding.
Blood- Anemia and sepsis.
Liver- Abnormal liver function.
Respiratory- Pneumonia.
Miscellaneous- Fever and infection.

What are the other precautions for Lepirudin?

Avoid alcohol consumption.

What are the storage conditions for Lepirudin?

Store it at controlled room temperature (2 to 25°C).

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