Levoleucovorin Medication Information

Discover comprehensive details about Levoleucovorin, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Levoleucovorin brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Levoleucovorin

Pronunciation : LEE-voe-LOO-koe-VOE-rin KAL-see-um

ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Brand Names or Trade Names of Levoleucovorin

International :

Levoleucovorin

Why is Levoleucovorin Prescribed? (Indications)

This medication is a folic acid derivative, used as an adjuvant in chemotherapy for treating patients with osteosarcoma and colorectal cancer. It helps to reduce the action and toxic effects of methotrexate.

When should Levoleucovorin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Levoleucovorin?

High-Dose Methotrexate in Osteosarcoma- 10 mg/sq.meter IV q6hr starting 24 hr after methotrexate
Coadministration with Trimetrexate- 20 mg/sq.meter IV/PO q6hr (for PO, round dose up to next 25 mg increment)
Colorectal CA- Recommended 20 mg/sq.meter IV followed by 425 mg/sq.meter fluorouracil.

How should Levoleucovorin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Levoleucovorin?

• Caution should be exercised in patients with history of anemia, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• Extreme caution needed for children less than 6 years old.

• Monitor serum creatinine level and complete blood counts regularly while taking this medication.

What are the side effects of Levoleucovorin?

Gastrointestinal - Mouth ulcer, vomiting, nausea, diarrhea, indigestion, and inflammation of intestine.
Respiratory - Difficulty in breathing.
Skin - Skin inflammation and hair loss.
Miscellaneous - Confusion, nerve disease, uneasiness, kidney impairment, taste perversion.