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Mechlorethamine HCl - Indications, Dosage, Side Effects and Precautions

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Mechlorethamine HCl Medication Information

Get detailed information on Mechlorethamine HCl, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Mechlorethamine HCl provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Mechlorethamine HCl
Pronunciation : meh-klor-ETH-ah-meen

Trade Names/Brand Names of Mechlorethamine HCl

International :


Mustargen

Why is Mechlorethamine HCl Prescribed? (Indications)

This medication is an anti-neoplastic agent, prescribed for Hodgkin's disease, non-Hodgkin's lymphoma along with other medications. It is also used as palliative chemotherapy in lung and breast cancers. It slows or stops the growth of cancer cells in the body.

When should Mechlorethamine HCl not be taken? (Contraindications)

Contraindicated in patients with infectious disease and known hypersensitivity.

What is the dosage of Mechlorethamine HCl?

IV- A total dose of 0.4 mg/kg usually is given either as a single dose or in divided doses of 0.1 to 0.2 mg/kg per day.

How should Mechlorethamine HCl be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Mechlorethamine HCl?

• It should not be administered via intradermal, subcutaneous, IM, intraarterial, or oral administration.

• Caution should be exercised in patients with blood/bleeding disorders, gout, current infection, kidney disease, liver disease, radiation treatment, any allergy, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption while taking this medication.

What are the side effects of Mechlorethamine HCl?

Skin - Hair loss, redness of the skin, herpes zoster; skin eruptions.
Eye and ENT - Diminished hearing, ringing in the ear, and fainting.
Gastrointestinal - Loss of appetite, diarrhea, nausea, vomiting.
Genitourinary - Decreased sperm count, impaired spermatogenesis, absence of menstrual period, delayed menses, increase in blood urea.
Blood - Bone marrow suppression and decrease in blood cells count.
Liver - Jaundice.
Miscellaneous - Chromosomal abnormalities, anaphylaxis.

What are the other precautions for Mechlorethamine HCl?

Avoid excess dosage.

What are the storage conditions for Mechlorethamine HCl?

Store at controlled room temperature (15-30°C). Protect from light and humidity.

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