Mercaptopurine Medication Information

Learn everything you need to know about Mercaptopurine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Mercaptopurine brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Mercaptopurine

Pronunciation : mer kap toe pyoor' een

ICD Code : Y43.1 Therapeutic Classification : Antimetabolites

Brand Names or Trade Names of Mercaptopurine

India :

More info >>>

International :

Purinethol.

Why is Mercaptopurine Prescribed? (Indications)

This medication is an antimetabolite, prescribed for acute lymphatic leukemia either alone or with other medications. It works by stopping the growth of cancer cells.

When should Mercaptopurine not be taken? (Contraindications)

Contraindicated in patients who have prior resistance to this drug, and hypersensitivity.

What is the dosage of Mercaptopurine?

Adult: PO- Acute lymphatic Leukemia: Usual maintenance dose: Initial: 1.5-2.5 mg/kg/day, may increase carefully up to 5 mg/kg/day.
Crohn's disease Initial: 1-1.5 mg/kg/day. Up to 125 mg/day.

How should Mercaptopurine be taken?

It comes as a tablet to take by mouth, on an empty stomach.

What are the warnings and precautions for Mercaptopurine?

• Caution should be exercised in patients with history of bone marrow problems, anemia, low white blood cell or platelet levels, unusual bruising or bleeding, liver or kidney problems, infections, any allergy, during pregnancy and breastfeeding.

• Avoid contact with people who have infections.

• It may reduce platelet counts; to prevent bleeding avoid injury or bruising.

• Patient may develop with increased risk other than cancer; if any unusual tumor appears consult with your doctor immediately.

• Avoid vaccination while taking this medication.

• Monitor blood cell counts, liver function tests, and TPMT enzyme activity regularly while taking this medication.

What are the side effects of Mercaptopurine?

Serious Effects - Bone marrow depression and liver damage.
Genitourinary - Abnormally elevated blood level of uric acid.
Gastrointestinal - Intestinal ulceration, nausea, vomiting, and loss of appetite.
Miscellaneous - Hair loss and decrease in sperm count.