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Muromonab CD 3 - Indications, Dosage, Side Effects and Precautions

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Information about Muromonab CD 3

Generic Name : Muromonab CD 3
Up-to-date prescription details regarding Muromonab CD 3 are provided here.

Pronunciation : MYOO-row-MOE-nab-CD Three

Learn the correct pronunciation of the Muromonab CD 3, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.4 Therapeutic Classification : Immunosuppressants

Trade Names/Brand Names of Muromonab CD 3

International :


Orthoclone OKT3

Why is Muromonab CD 3 Prescribed? (Indications)

This medication is an immunosuppressant, prescribed for organ rejection. The immune system helps the body fight infections.

When should Muromonab CD 3 not be taken? (Contraindications)

Contraindicated in patients with an allergy against mouse proteins, heart failure, uncontrolled hypertension, epilepsy, during pregnancy and breastfeeding.

What is the dosage of Muromonab CD 3?

The recommended dose is 5 mg per day in a single (bolus) intravenous injection in less than one minute for 10 to 14 days.

How should Muromonab CD 3 be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Muromonab CD 3?

• Caution should be exercised in patients with history of fever or infection, swelling, high/low blood electrolyte levels, stroke, seizures, heart attack, any allergy, who are taking other medications, head injury, elderly and children.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Patient may develop with certain types of cancer with the following symptoms: unusual lumps or skin thickenings, growths or color changes. If it is so consult with your doctor.

• Monitor kidney and liver function, blood pressure, blood counts, blood electrolytes and weight regularly while taking this medication.

• Avoid contact with people having infections.

What are the side effects of Muromonab CD 3?

Autonomic Nervous System - Excessive sweating and dilatation of blood vessels.
Body as a Whole - Loss of appetite, weakness, fever, chills, fatigue, lethargy, uneasiness, pain.
Heart - Abnormal heart rhythm, slow/fast heart rate, high/low blood pressure and chest pain.
Central Nervous System - Convulsions, dizziness, headache and tremor.
Gastrointestinal - Diarrhea, nausea, abdominal pain and vomiting.
Blood - Anemia, decrease in white blood cells and platelets.
Metabolic - Swelling in the legs.
Musculoskeletal - Joint pain and muscle pain.
Psychiatric - Confusion, depression, nervousness and drowsiness.
Genitourinary - Kidney damage.
Respiratory - Abnormal chest sound, difficulty in breathing, fast breathing, lung swelling and wheezing.
Skin - Itching, rash and redness.
Eye and ENT - Sensitivity to light and ringing in the ear.

What are the other precautions for Muromonab CD 3?

Avoid excess dosage.

What are the storage conditions for Muromonab CD 3?

Store unopened vials in refrigerator (36° to 46° F). Avoid shaking or freezing of medicine.
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