Nimotuzumab Medication Information

Get detailed information on Nimotuzumab, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Nimotuzumab provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Nimotuzumab

Pronunciation : Ni-motu-zu-mab

Therapeutic Classification : Monoclonal antibodies

Trade Names/Brand Names of Nimotuzumab

India :

Biomab EGFR

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Overview of Nimotuzumab

• Nimotuzumab is used for the treatment of glioma (cancer in brain and spinal cord).

Why is Nimotuzumab Prescribed? (Indications)

Nimotuzumab is a monoclonal antibody and an endothelial growth factor receptor (EGRF) antagonist.
It also stimulates the immune system against the cancer cells.

It is a targeted therapy used for the treatment of glioma (cancer in the brain and spinal cord), cancer of the head and neck, and nasopharyngeal cancer.
It prevents the growth and spread of the cancer.

The drug is approved for different cancers in different countries.
It has received orphan drug status for the treatment of glioma in the United States and pancreatic cancer in the European Union.

When should Nimotuzumab not be taken? (Contraindications)

• The drug is contraindicated if the patient is allergic to drug, or during pregnancy and breastfeeding in women.

What is the dosage of Nimotuzumab?

• The recommended dose of the drug in adults is 200 mg as a continuous intravenous infusion weekly with combination of radiation therapy for 6 weeks followed by 200 mg every 15 days as maintenance treatment.

How should Nimotuzumab be taken?

• Nimotuzumab should be administered diluted in 0.9% sodium chloride over 60 minutes in adults.

What are the warnings and precautions for Nimotuzumab?

• The drug should be administered with caution in the patients with diabetes, heart disease or hypertension.

• The antihistamine diphenhydramine should be administered before the infusion to prevent a reaction.

• Use with caution in patients who were previously treated with the murine monoclonal antibody.

What are the side effects of Nimotuzumab?

Gastrointestinal: Nausea, vomiting
Skin: Skin rash
Cardiovascular: Changes in blood pressure
Central nervous system: Drowsiness, disorientation
Others: Fever, chills, rigors, weakness, allergic reaction, blood in the urine, increase in liver enzymes

What are the other precautions for Nimotuzumab?

• Do not shake the vial.
• Inspect the vial for particulate matter and discoloration before use. Discard if present.

What are the Drug Interactions of Nimotuzumab?

• Not known.

What are the storage conditions for Nimotuzumab?

• Nimotuzumab should be stored under refrigeration at 2-8°C. Do not freeze.
• The diluted solution can be kept at room temperature between 22-27°C for up to 72 hours.