Ofatumumab Medication Information

Discover comprehensive details about Ofatumumab, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Ofatumumab brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Ofatumumab

Pronunciation : oh-fuh-TOO-muh-mab

ICD Code : Y43.4 Therapeutic Classification : Monoclonal antibodies

Brand Names or Trade Names of Ofatumumab

International :

Arzerra

Why is Ofatumumab Prescribed? (Indications)

This medication is a human monoclonal antibody, prescribed for chronic lymphocytic leukemia (CLL). It works by killing cancer cells.

When should Ofatumumab not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Ofatumumab?

The recommended dose and schedule is 12 doses administered as follows:
* 300 mg initial dose (Dose 1), followed 1 week later by.
* 2,000 mg weekly for 7 doses (Doses 2 through 8), followed 4 weeks later by.
* 2,000 mg every 4 weeks for 4 doses (Doses 9 through 12).

How should Ofatumumab be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Ofatumumab?

• Caution should be exercised in patients with history of chronic obstructive pulmonary disease (COPD), bowel obstruction, decrease in white blood cells, flu-like symptoms, hepatitis, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Avoid live vaccination during the treatment period.

• Avoid contact with people who have infections.

• It may reduce platelet counts; avoid injury or bruising.

• Patient may develop with increased risk of certain types of viral brain infection (progressive multifocal leukoencephalopathy [PML]) with the following symptoms: confusion, dizziness, difficulty in talking or walking, abnormal thinking, poor eyesight, imbalance, or weakness. If it is so consult with your doctor immediately.

What are the side effects of Ofatumumab?

Most Common - Decrease in white blood cells, pneumonia, fever, cough, diarrhea, anemia, fatigue, difficulty in breathing, rash, nausea, vomiting, lung inflammation, and upper respiratory tract infections.
Central Nervous system - Sleeplessness and headache.
Heart - High/low blood pressure and fast heart rate.
Respiratory - Cough.
Skin - Rash, hives and increased sweating.
Musculoskeletal - Back pain and muscle spasms.
General - Swelling in the extremities and chills.