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Pentobarbital - Indications, Dosage, Side Effects and Precautions

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Pentobarbital Medication Information

Learn everything you need to know about Pentobarbital-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Pentobarbital brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Pentobarbital
Pronunciation : pen toe bar' bi tal
ICD Code : Y47.0 Therapeutic Classification : Sedative-hypnotic Drugs

Brand Names or Trade Names of Pentobarbital

International :


Nembutal

Why is Pentobarbital Prescribed? (Indications)

This medication is a barbiturate, prescribed for insomnia and seizures.  It slows the activities of brain and nervous system.

When should Pentobarbital not be taken? (Contraindications)

Contraindicated in patients with history of manifest or latent porphyria (hidden genetic disorder) and hypersensitivity.

What is the dosage of Pentobarbital?

Dose is based patient’s condition.
IM- Adult- The recommended dosage ranges from 50 to 200 mg as a single dose.
Child- The recommended dosage ranges from 2 to 6 mg/kg as a single dose; Maximum- 100 mg.
IV- The recommended initial dose for the 70 kg adult is 100 mg.

How should Pentobarbital be taken?

It comes as a solution for injection to be administered by a healthcare provider into the large muscle or into the vein.

What are the warnings and precautions for Pentobarbital?

• Caution should be exercised in patients with history of liver or kidney disease, asthma, hyperthyroidism, diabetes, anemia, history of alcoholism or drug abuse, heart or lung problems, any allergy, who are taking other medications, children, elderly, during pregnancy and breastfeeding.

• Avoid rapid intravenous administration; otherwise it may cause respiratory depression.

• Avoid long-term use of this medication; otherwise patient may get addicted to this drug.

• Avoid alcohol consumption.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pentobarbital?

Most Common - Drowsiness.
Central Nervous system - Agitation, confusion, incoordiation, depression, abnormal dreams, nervousness, mental disturbances, hallucinations, sleeplessness, anxiety, dizziness and thinking abnormality.
Respiratory - Respiratory depression and shortness of breathing.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Hypersensitivity reactions - Shock, skin rashes and skin inflammation.
Miscellaneous - Headache, injection site reactions, fever, liver damage and anemia

What are the other precautions for Pentobarbital?

Avoid excess dosage.

What are the storage conditions for Pentobarbital?

Store it at controlled room temperature (15-30°C).

Schedule : X
Narcotic and Psychotropic drugs which cannot be sold without the prescription of a Registered Medical Practitioner.

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