Information about Pethidine

Generic Name : Pethidine
Up-to-date prescription details regarding Pethidine are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y45.0 Therapeutic Classification : Analgesics

Trade Names/Brand Names of Pethidine

India :

Pethidine Hcl (100 mg) | Pethidine | Pethidine Hcl

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International :

Pethiscot

Why is Pethidine Prescribed? (Indications)

This medication is an opioid analgesic, prescribed for moderate to severe pain, for example labor pain, before and during a surgical operation. It changes the way the body senses pain.

When should Pethidine not be taken? (Contraindications)

Contraindicated to pregnant and breastfeeding women.

What is the dosage of Pethidine?

Adult: PO- Moderate to severe acute pain -50-150 mg 4 hourly.
IV- Adjunct to anesthetic- 10-25 mg.
IV/IM/SC- Moderate to severe acute pain- 25-100 mg 4 hourly.
IM/SC- Obstetric analgesia- 50-100 mg as soon as contractions occur at regular intervals; repeat after 1-3 hr if needed. Max: 400 mg/24 hour.
Pre-op medication 25-100 mg 1 hour pre-op.
Post-op pain-25-100 mg 2-3 hourly if needed.

How should Pethidine be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein or large muscle.

What are the warnings and precautions for Pethidine?

• Caution should be exercised in patients with history of severe respiratory problems, fits, head injuries, increased eye pressure, heart or liver problems, diabetes, depression, genetic disorder, any allergy, who are taking other medications, elderly and children.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid abrupt withdrawal.

What are the side effects of Pethidine?

Most Common- Nausea, vomiting, constipation, drowsiness, dizziness, dry mouth and sweating.
Central Nervous System- Nervousness, headache, restlessness, uneasiness, fatigue, confusion, depression, hallucinations, tremors, muscle twitches, increased intracranial pressure and fits.
Skin- Rash and hives.
Gastrointestinal- Loss of appetite, stomach cramps, muscle spasm and spincture muscle dysfunction.
Miscellaneous- Weakness, decreased urination, difficulty in breathing and pain at injection site.