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Pethidine - Indications, Dosage, Side Effects and Precautions

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Pethidine Medication Information

Discover comprehensive details about Pethidine, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Pethidine brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Pethidine
ICD Code : Y45.0 Therapeutic Classification : Analgesics

Brand Names or Trade Names of Pethidine

India :

International :


Pethiscot

Why is Pethidine Prescribed? (Indications)

This medication is an opioid analgesic, prescribed for moderate to severe pain, for example labor pain, before and during a surgical operation.  It changes the way the body senses pain.

When should Pethidine not be taken? (Contraindications)

Contraindicated to pregnant and breastfeeding women.

What is the dosage of Pethidine?

Adult: PO- Moderate to severe acute pain -50-150 mg 4 hourly.
IV- Adjunct to anesthetic- 10-25 mg.
IV/IM/SC- Moderate to severe acute pain- 25-100 mg 4 hourly.
IM/SC- Obstetric analgesia- 50-100 mg as soon as contractions occur at regular intervals; repeat after 1-3 hr if needed. Max: 400 mg/24 hour.
Pre-op medication 25-100 mg 1 hour pre-op.
Post-op pain-25-100 mg 2-3 hourly if needed.

How should Pethidine be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein or large muscle.

What are the warnings and precautions for Pethidine?

• Caution should be exercised in patients with history of severe respiratory problems, fits, head injuries, increased eye pressure, heart or liver problems, diabetes, depression, genetic disorder, any allergy, who are taking other medications, elderly and children.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid abrupt withdrawal.

What are the side effects of Pethidine?

Most Common- Nausea, vomiting, constipation, drowsiness, dizziness, dry mouth and sweating.
Central Nervous System- Nervousness, headache, restlessness, uneasiness, fatigue, confusion, depression, hallucinations, tremors, muscle twitches, increased intracranial pressure and fits.
Skin- Rash and hives.
Gastrointestinal- Loss of appetite, stomach cramps, muscle spasm and spincture muscle dysfunction.
Miscellaneous- Weakness, decreased urination, difficulty in breathing and pain at injection site.

What are the other precautions for Pethidine?

Avoid alcohol consumption while taking this medication.
Avoid excess dosage.

What are the storage conditions for Pethidine?

Store it at room temperature (15°- 25° C). Do not freeze and protect from light.

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