Physostigmine Medication Information

Get detailed information on Physostigmine, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Physostigmine provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Physostigmine

Pronunciation : fye-soe-STIG-meen

ICD Code : Y51.0 Therapeutic Classification : Anticholinergic antidotes

Trade Names/Brand Names of Physostigmine

India :

Bi-Miltic | Bi Miotic

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International :

Antilirium, Eserine Salicylate, Isopto Eserine, and Eserine Sulfate

Why is Physostigmine Prescribed? (Indications)

This medication is a reversible cholinesterase inhibitor alkaloid, prescribed for reversal of anticholinergic toxicity. It increases the amount of fluid that drains from the eye.

When should Physostigmine not be taken? (Contraindications)

It should not be used in patients with asthma, gangrene, diabetes, heart disease, obstruction of the intestine or urogenital tract, in patients receiving choline esters and depolarizing neuromuscular blocking agents.

What is the dosage of Physostigmine?

Dosage: Adults- IV- 0.5 to 1 mg infused over at least 5 min; repeat in 10 to 15 min as clinically indicated.
Children- IV- 0.02 mg/kg (up to 0.5 mg) infused over at least 5 min; repeat in 10 to 15 min as clinically indicated (up to a total dose of 2 mg).
Post anesthesia care- Adults- IV/IM- 0.5 to 1 mg; repeat at intervals of 10 to 30 min as clinically indicated.

How should Physostigmine be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Physostigmine?

• Caution should be exercised in patients with history of QT prolongation, during pregnancy and breastfeeding.

• Patient may develop with severe allergic reactions; Keep atropine in hand to treat.