Physostigmine Medication Information

Learn everything you need to know about Physostigmine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Physostigmine brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Physostigmine

Pronunciation : fye-soe-STIG-meen

ICD Code : Y51.0 Therapeutic Classification : Anticholinergic antidotes

Brand Names or Trade Names of Physostigmine

India :

Bi-Miltic | Bi Miotic

More info >>>

International :

Antilirium, Eserine Salicylate, Isopto Eserine, and Eserine Sulfate

Why is Physostigmine Prescribed? (Indications)

This medication is a reversible cholinesterase inhibitor alkaloid, prescribed for reversal of anticholinergic toxicity. It increases the amount of fluid that drains from the eye.

When should Physostigmine not be taken? (Contraindications)

It should not be used in patients with asthma, gangrene, diabetes, heart disease, obstruction of the intestine or urogenital tract, in patients receiving choline esters and depolarizing neuromuscular blocking agents.

What is the dosage of Physostigmine?

Dosage: Adults- IV- 0.5 to 1 mg infused over at least 5 min; repeat in 10 to 15 min as clinically indicated.
Children- IV- 0.02 mg/kg (up to 0.5 mg) infused over at least 5 min; repeat in 10 to 15 min as clinically indicated (up to a total dose of 2 mg).
Post anesthesia care- Adults- IV/IM- 0.5 to 1 mg; repeat at intervals of 10 to 30 min as clinically indicated.

How should Physostigmine be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Physostigmine?

• Caution should be exercised in patients with history of QT prolongation, during pregnancy and breastfeeding.

• Patient may develop with severe allergic reactions; Keep atropine in hand to treat.