Information about Ponatinib

Generic Name : Ponatinib
Up-to-date prescription details regarding Ponatinib are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Ponatinib

International :

Iclusig

Why is Ponatinib Prescribed? (Indications)

This medication is a human monoclonal antibody (kinase inhibitor), prescribed for chronic myeloid leukemia (CML).

What is the dosage of Ponatinib?

PO- The recommended dose is 45mg once daily.

How should Ponatinib be taken?

It comes a tablet to take by mouth, with or without food.

What are the warnings and precautions for Ponatinib?

• Caution should be exercised in patients with history of blood clots, heart, liver or kidney problems, pancreatitis, high blood pressure, bleeding problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Monitor complete blood count, patients for fluid retention, heart rhythm, blood pressure, signs and symptoms of heart failure regularly while taking this medication.

• Ensure adequate hydration otherwise it may lead to dehydration.

What are the side effects of Ponatinib?

Most Common - High blood pressure, rash, abdominal pain, fatigue, headache, dry skin, constipation, joint pain, nausea and fever.
Blood - Anemia, decrease in white blood cells and platelets.
Miscellaneous - Myelosuppression, abnormal heart rhythm and fluid retention.
Heart - Heart Failure.
Gastrointestinal - Constipation, nausea, diarrhea, vomiting, mouth ulcer, GI hemorrhage.
Infection - Pneumonia, urinary tract infection, upper respiratory tract infection.
Central Nervous system - Peripheral neuropathy, dizziness.
Respiratory - Pleural effusion, cough, difficulty in breathing.
Skin - Rash, dry skin.
Musculoskeletal - Joint and muscle pain, pain in extremity, back pain, muscle spasms, bone pain.
General - Weakness.