Ponatinib Medication Information

Learn everything you need to know about Ponatinib-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Ponatinib brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Ponatinib

Brand Names or Trade Names of Ponatinib

International :

Iclusig

Why is Ponatinib Prescribed? (Indications)

This medication is a human monoclonal antibody (kinase inhibitor), prescribed for chronic myeloid leukemia (CML).

What is the dosage of Ponatinib?

PO- The recommended dose is 45mg once daily.

How should Ponatinib be taken?

It comes a tablet to take by mouth, with or without food.

What are the warnings and precautions for Ponatinib?

• Caution should be exercised in patients with history of blood clots, heart, liver or kidney problems, pancreatitis, high blood pressure, bleeding problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Monitor complete blood count, patients for fluid retention, heart rhythm, blood pressure, signs and symptoms of heart failure regularly while taking this medication.

• Ensure adequate hydration otherwise it may lead to dehydration.

What are the side effects of Ponatinib?

Most Common - High blood pressure, rash, abdominal pain, fatigue, headache, dry skin, constipation, joint pain, nausea and fever.
Blood - Anemia, decrease in white blood cells and platelets.
Miscellaneous - Myelosuppression, abnormal heart rhythm and fluid retention.
Heart - Heart Failure.
Gastrointestinal - Constipation, nausea, diarrhea, vomiting, mouth ulcer, GI hemorrhage.
Infection - Pneumonia, urinary tract infection, upper respiratory tract infection.
Central Nervous system - Peripheral neuropathy, dizziness.
Respiratory - Pleural effusion, cough, difficulty in breathing.
Skin - Rash, dry skin.
Musculoskeletal - Joint and muscle pain, pain in extremity, back pain, muscle spasms, bone pain.
General - Weakness.