Pooled Plasma (Human) Medication Information
Discover comprehensive details about Pooled Plasma (Human), including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.
The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.
Additionally, explore the Pooled Plasma (Human) brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.
Generic Name : Pooled Plasma (Human)Brand Names or Trade Names of Pooled Plasma (Human)
International :
Octaplas
Why is Pooled Plasma (Human) Prescribed? (Indications)
This medication is a solvent/ detergent (S/D) treated, liquid component of whole blood, collected and pooled to prepare various plasma products or to use directly as a plasma expander when whole blood is unavailable or is contraindicated. It is used as a replacement of multiple coagulation factors in patients with acquired deficiencies due to liver disease undergoing cardiac surgery or liver transplant. It also used as plasma exchange in patients with thrombotic thrombocytopenic purpura (TTP) and replacement of coagulation factors for other medical conditions.When should Pooled Plasma (Human) not be taken? (Contraindications)
Contraindicated in patients undergoing liver transplant, patients with severe liver disease and known coagulopathies.What is the dosage of Pooled Plasma (Human)?
Intravenous use based on AB0-blood group compatibility. Solution for infusion containing 45 to 70 mg human plasma protein per mL in a 200 mL volume.10 to 15 mL per kg for replacement of multiple coagulation factors in patients with acquired deficiencies.
40 to 60 milliliters per kg for plasma exchange in patients with TTP.
How should Pooled Plasma (Human) be taken?
It comes as a solution for infusion.What are the warnings and precautions for Pooled Plasma (Human)?
• Patients receiving large volumes of pooled plasma to be monitored for evidence of thrombosis, excessive bleeding, or exacerbation of DIC.• Use only if clearly needed during pregnancy.
• Transfusion reactions can occur with AB0 blood group mismatches.
• High infusion rates can induce hypervolemia with consequent pulmonary edema or cardiac failure.
• Thrombosis can occur due to low levels of Protein S.
• The pooled plasma is made from human blood; therefore, may carry the risk of transmitting infectious agents, e.g., viruses and theoretically, the variant Creutzfeldt-Jakob disease.
What are the side effects of Pooled Plasma (Human)?
Itching, hives, fever, chills, abdominal or back pain, nausea, headache, tingling, anaphylactic shock, citrate toxicity, severe hypotension.What are the other precautions for Pooled Plasma (Human)?
Pooled plasma should not be mixed with other medicinal products as inactivation and precipitation may occur.Avoid shaking and do not use solutions, which are cloudy or have deposits.
