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Pralatrexate Solution - Indications, Dosage, Side Effects and Precautions

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Pralatrexate Solution Medication Information

Discover comprehensive details about Pralatrexate Solution, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Pralatrexate Solution brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Pralatrexate Solution
Pronunciation : PRAL-a-TREX-ate

Brand Names or Trade Names of Pralatrexate Solution

International :


Folotyn

Why is Pralatrexate Solution Prescribed? (Indications)

This medication is a folate analogue metabolic inhibitor, prescribed for refractory peripheral T-cell lymphoma (PTCL). It works by killing certain types of cancer cells.

When should Pralatrexate Solution not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Pralatrexate Solution?

IV- The recommended dose is 30 mg/m2 over 3-5 minutes infusion.

How should Pralatrexate Solution be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Pralatrexate Solution?

• Caution should be exercised in patients with history of liver or kidney impairment, any allergy, children, during pregnancy and breastfeeding.

Avoid use in patients with end stage renal disease including those undergoing dialysis.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid becoming dehydrated while taking this medication.

• Monitor complete blood cell counts and liver and kidney function regularly while taking this medication.

• Patient may develop with increased risk of tumor lysis syndrome (TLS) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, nausea, vomiting, diarrhea, or loss of appetite; or sluggishness. If it is so consult with your doctor.

What are the side effects of Pralatrexate Solution?

Most Common - Decrease in platelet counts and white blood cells, inflammation of mucous, nausea, fatigue, anemia, constipation, fever, fluid retention, cough, nose bleed, vomiting, diarrhea, difficulty in breathing, loss of appetite, rash, itching, throat pain, liver function test abnormal, abdominal pain, pain in extremity, back pain, night sweats, weakness, fast heart rate.

What are the other precautions for Pralatrexate Solution?

Avoid excess dosage.

What are the storage conditions for Pralatrexate Solution?

Store in refrigerator at 2-8°C.

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