Pralsetinib Medication Information
Get detailed information on Pralsetinib, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Pralsetinib provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Pralsetinib Pronunciation : pralTrade Names/Brand Names of Pralsetinib
India :
Gavreto
Overview of Pralsetinib
Pralsetinib is an anticancer agent indicated for the treatment of adults with non-small cell lung cancer (NSCLC), based on the presence of a specific gene fusion named RET.Why is Pralsetinib Prescribed? (Indications)
Pralsetinib is indicated for the treatment of adults with non-small cell lung cancer (NSCLC), based on the presence of a specific gene fusion named RET.When should Pralsetinib not be taken? (Contraindications)
Patients allergic to PralsetinibWhat is the dosage of Pralsetinib?
Pralsetinib is available as an oral capsule in the following dose:• 100mg
How should Pralsetinib be taken?
The recommended dosage in adults is 400 mg orally once daily on an empty stomachFood intake is not recommended for at least 2 hours before and at least 1 hour after taking Pralsetinib.
Missed a Dose?
If a planned dose of Pralsetinib is missed, take the dose as soon as possible on the same day. Resume the daily dose schedule for the next day.What are the warnings and precautions for Pralsetinib?
• Pregnant and lactating women should not use this drug• The drug may impair fertility in males and females of reproductive potential
• Female patients with reproductive potential should use effective contraception during treatment and for 1 week after the final dose.
• Males with female partners of reproductive potential should use effective contraception during treatment and for 1 week after the final dose
What are the side effects of Pralsetinib?
•General: Tiredness, decreased white blood cells, hemoglobin, sodium, phosphate, decreased calcium•Heart: Hypertension
•Digestive: Constipation, increased liver enzymes
•Joints: Joint pain
What are the other precautions for Pralsetinib?
•Patients should report to a health provider if there are new or worsening respiratory symptoms – the drug may cause pneumonia.•Patients should be monitored for blood pressure regularly.
•The drug may impair wound healing. Temporary interruption of the drug is recommended prior to any elective surgery
•The drug may cause liver problems. Monitor regularly the liver function tests during and after treatment.
•The drug may decrease the levels of phosphate. So phosphate levels are to be monitored regularly.
What are the Drug Interactions of Pralsetinib?
Pralsetinib should not be given along with inhibitors or inducers of CYP3A4.Reduce dose from 400 mg and 300 mg to 200 mg and from 200 mg to 100 in case of the concomitant administration with inhibitors of CYP3A4.
