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Probenecid - Indications, Dosage, Side Effects and Precautions

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Probenecid Medication Information

Learn everything you need to know about Probenecid-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Probenecid brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Probenecid
Pronunciation : proe ben' e sid
Therapeutic Classification : Gout Therapy

Brand Names or Trade Names of Probenecid

India :

International :


Benemid

Why is Probenecid Prescribed? (Indications)

This medication is a uricosuric agent, prescribed for chronic gout and gouty arthritis. It increases the excretion of uric acid from the body.

When should Probenecid not be taken? (Contraindications)

Contraindicated in children under 2 years of age, persons with known blood dyscrasias, kidney stone, hypersensitivity, during pregnancy and breastfeeding.

What is the dosage of Probenecid?

PO- The usual adult dose for hyperuricemia is 500 mg twice daily and the maximum dose is 2 grams daily.

How should Probenecid be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Probenecid?

• Caution should be exercised in patients with history of ulcers, kidney stones,kidney disorder, blood disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may affect blood sugar level, monitor sugar level regularly.

What are the side effects of Probenecid?

Central Nervous System - Headache and dizziness.
Metabolic - Precipitation of acute gouty arthritis.
Gastrointestinal - Liver damage, vomiting, nausea, loss of appetite and sore gums.
Genitourinary - Kidney damage, blood in urine, kidney stone, back pain and urinary frequency.
Hypersensitivity - Shock, fever, hives and itching.
Blood - Anemia and decrease in white blood cells.
Skin - Skin inflammation, hair loss and flushing.

What are the other precautions for Probenecid?

Drink adequate fluid especially during the first few months of treatment.

What are the storage conditions for Probenecid?

Store it at room temperature (20°-25°C).

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