Proguanil Medication Information

Discover comprehensive details about Proguanil, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Proguanil brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Proguanil

Pronunciation : proe-GWAHN-il

ICD Code : Y41.2 Therapeutic Classification : Anti- Malarials

Brand Names or Trade Names of Proguanil

India :

Progunal | Laveran

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International :

Malarone- Atovaquone +Proguanil

Why is Proguanil Prescribed? (Indications)

This medication is an antiprotozoal and antimalarial, prescribed for prevention of malaria, treatment of malaria. It prevents the development of malaria parasites.

When should Proguanil not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, severe kidney failure.

What is the dosage of Proguanil?

Adult: PO- Malaria prophylaxis- 200 mg/day with chloroquine or 100 mg/day with atovaquone. Start 1 week before exposure to malaria or 1-2 days prior to travel. Continue throughout exposure and for at least 4 week (or 1 week if given with atovaquone) after leaving a malaria-infested area.

How should Proguanil be taken?

It comes as a tablet to take by mouth (orally), with food.

What are the warnings and precautions for Proguanil?

•It may not work as well if you have severe or persistent vomiting or diarrhea.

It may make you drowsy. Do not drive a car or operate machinery while taking this medication.

Caution needed for patients with history of kidney disease, pregnancy, breast feeding, elderly, and children.

• If you experience with vomiting within one hour after taking this medication, take another dose.

What are the side effects of Proguanil?

Most Common in adult- Abdominal pain, nausea, vomiting, headache, diarrhea, weakness, loss of appetite, and dizziness.
Children- Vomiting, and itching.
Kidney- Blood in urine.
Blood - Abnormally decrease in white blood cells, and rarely anemia. Decrease in all types of blood cells.
Allergic reactions- Allergic reactions including rapid swelling, hives, rare cases of life-threatening allergies, and inflammation of blood vessels.
Central Nervous System - Rarely seizures and hallucinations.
Gastrointestinal - Mouth ulcer.
Liver- Elevated liver function tests and rare cases of liver inflammation.
Skin - Photosensitivity, rash, and rare cases of erythema multiforme and Stevens-Johnson syndrome.