Information about Promethazine

Generic Name : Promethazine
Up-to-date prescription details regarding Promethazine are provided here.

Pronunciation : proe meth' a zeen

Learn the correct pronunciation of the Promethazine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y43.0 Therapeutic Classification : Antiemetics

Trade Names/Brand Names of Promethazine

India :

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International :

Phenergan, Promacot, Promethegan

Overview of Promethazine

Note: This brand is not available in US market.

Why is Promethazine Prescribed? (Indications)

This medication is an antihistamine and antiemetic, prescribed for allergic conditions, prevention of motion sickness, and to control nausea and vomiting during and after surgery. It controls nausea and vomiting by changing the actions of chemicals in brain.

When should Promethazine not be taken? (Contraindications)

Contraindicated in patients with asthma, children less than 2 years, and hypersensitivity.
Avoid subcutaneous administration.

What is the dosage of Promethazine?

Allergy- The average oral dose is 25 mg taken before retiring; however, 12.5 mg may be taken before meals and on retiring, if necessary.
Motion Sickness- The average adult dose is 25 mg taken twice daily. The initial dose should be taken one-half to one hour before anticipated travel and be repeated 8 to 12 hours later, if necessary.
Nausea and Vomiting- Adults- The recommended dosage is 25 mg.

How should Promethazine be taken?

It comes as a tablet, capsule, liquid to take by mouth, with or without food.
It also comes as rectal suppositories, to insert through the rectum.

What are the warnings and precautions for Promethazine?

• Caution should be exercised in patients with history of nervous system problems, bone marrow depression, heart problems, blood disease, increased eye pressure, low blood pressure, liver disease, ulcers, urinary obstruction, enlarged prostate, Parkinson disease, seizures, Reye syndrome, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, or blurred vision, do not drive a car operate machinery while taking this medication.

• Avoid alcohol consumption.

• Patient may develop with increased risk of tissue injury, seizures and Neuroleptic malignant syndrome (NMS); if it is so consult with your doctor.

What are the side effects of Promethazine?

Central Nervous System - Drowsiness, blurred vision, dizziness, confusion, disorientation, weakness, ringing in the ear, incoordination, fatigue, emotion, nervousness, double vision, sleeplessness, tremors, convulsive seizures, excitement and hallucinations.
Heart - Increased or decreased blood pressure, fast/slow heart rate and faintness.
Skin - Skin inflammation, sensitivity to light and hives.
Blood - Bruising, decrease in white blood cells and platelets.
Gastrointestinal - Dry mouth, nausea, vomiting and jaundice.
Respiratory - Asthma, nasal stuffiness and respiratory depression.