Prucalopride Medication Information

Discover comprehensive details about Prucalopride, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Prucalopride brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Prucalopride

Pronunciation : proo-KAL-oh-pride.

Brand Names or Trade Names of Prucalopride

India :

Motegrity

Overview of Prucalopride

Prucalopride is a prescription medicine used in adults to treat chronic idiopathic constipation (CIC).
Chronic means long standing. Idiopathic means the cause is unknown.

Why is Prucalopride Prescribed? (Indications)

Prucalopride is a serotonin agonist (acts like serotonin in our body), used for the treatment of chronic idiopathic constipation (CIC) in adults.

When should Prucalopride not be taken? (Contraindications)

Prucalopride is contraindicated in patients with:

• Allergy to Prucalopride or any of the components in Prucalopride
• Intestinal perforation (bowel tear)
• Obstructive ileus (bowel block)
• Crohn’s disease, ulcerative colitis
• Toxic megacolon

What is the dosage of Prucalopride?

Prucalopride is available as tablets containing 1 mg or 2mg Prucalopride.

How should Prucalopride be taken?

1. The recommended dose of prucalopride is 2 mg once daily for adults with or without food.
2. The dose is 1mg once daily for adults with renal impairment (creatinine clearance less than 30 mL/min)

What are the warnings and precautions for Prucalopride?

•Monitor patients for any increase in depression and emergence of suicidal thoughts and behavior. In this case, instruct patients to discontinue prucalopride immediately and contact their doctor.

What are the side effects of Prucalopride?

• Gastrointestinal: Abdominal pain, Nausea, , Vomiting , Diarrhea , Abdominal distension, Flatulence (bloating sensation and gas formation)
• Nervous system: Headache, Dizziness, Fatigue (tiredness)

What are the other precautions for Prucalopride?

Inform your doctor if you have:

• Depression, suicidal thoughts or disorders
• Kidney problems
• Pregnant or planning to become pregnant
• Breastfeeding or planning to breastfeed
• All the drugs you are taking at present

What are the Drug Interactions of Prucalopride?

Prucalopride reacts rarely with the following drugs and the interaction is not much significant:

• Erythromycin
• Warfarin
• Digoxin
• Paroxetine
• Ethinyl estradiol
• Norethisterone
• Ketoconazole