Pyrimethamine- Sulfadoxine Medication Information
Get detailed information on Pyrimethamine- Sulfadoxine, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Pyrimethamine- Sulfadoxine provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Pyrimethamine- Sulfadoxine Pronunciation : peer-i-METH-a-meen - sul-fa-DOX-een ICD Code : Y41.2 Therapeutic Classification : Anti- MalarialsTrade Names/Brand Names of Pyrimethamine- Sulfadoxine
India :
Rimodar F T |
Reziz (10ml) |
Pyrima F A |
Pyralfin Forte |
Croydoxin F M |
Reziz |
M -2 |
Maladox |
Amalar (750 mg) |
Falcipar
International :
Fansidar
Why is Pyrimethamine- Sulfadoxine Prescribed? (Indications)
This medication is an antimalarial agent, prescribed for treatment of falciparum malaria, resistant to chloroquine. It blocks the formation of folinic acid within the malaria organism, which kills the parasite.When should Pyrimethamine- Sulfadoxine not be taken? (Contraindications)
Contraindicated in patients with severe kidney or liver failure, blood disorder, hypersensitivity to components, megaloblastic anemia due to folic acid deficiency, pregnancy at term and during lactation, infants ≤ 2 month old.What is the dosage of Pyrimethamine- Sulfadoxine?
PO- The recommended single dose is 3 tabs (sulfadoxine/ pyrimethamine 500 mg /25 mg), take next dose after 7 days, if needed.How should Pyrimethamine- Sulfadoxine be taken?
It comes as a tablet to take by mouth, after food.What are the warnings and precautions for Pyrimethamine- Sulfadoxine?
•Caution should be exercised in patients with history of liver or kidney failure, folic acid deficiency, severe allergy or bronchial asthma, G6PD deficiency, pregnancy.• Take with plenty of water to prevent crystal or stone formation in the urinary tract.
Avoid excessive exposure to sun.
• Regular laboratory testing of blood counts, urine and liver functions should be carried out.
• Take with food to minimize GI effects (e.g. anorexia and vomiting).
What are the side effects of Pyrimethamine- Sulfadoxine?
Blood- Decrease in white blood cells, bone marrow depression, decrease in platelets, anemia, bruising, poor blood clot, methemoglobinemia, and increase in eosinophils.Allergic Reactions- Rash, itching, swelling, dizziness, trouble breathing.
Skin- Severe allergic reactions, hair loss.
Eye- Photosensitivity, swelling in the eye.
Gastrointestinal - Inflammation of tongue, mouth infection, nausea, vomiting, abdominal pains, diarrhea, inflammation of liver or pancreas, feeling of fullness, and transient rise of liver enzymes.
Central Nervous System - Depression, headache, hallucinations, fatigue, nervousness, fainting. Sleeplessness, inflammation of nerves, involuntary movements, emotion, muscle weakness.
Respiratory- Pulmonary infiltrates resembling eosinophilic or lung inflammation.
Genitourinary- Kidney failure, interstitial nephritis, decreased urination, and crystals in urine.
Miscellaneous - Drug fever, chills, and LE phenomenon have occurred.
What are the other precautions for Pyrimethamine- Sulfadoxine?
Take full course of treatment.If there is no improvement in your health condition or if they become worse consult with your doctor.
