Regorafenib Medication Information

Discover comprehensive details about Regorafenib, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Regorafenib brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Regorafenib

Brand Names or Trade Names of Regorafenib

International :

Stivarga

Why is Regorafenib Prescribed? (Indications)

This medication is a kinase inhibitor, prescribed for metastatic colorectal cancer (CRC) in patients who have been previously treated with fluoropyrimidine- oxaliplatin-and irinotecan-based chemotherapy. It works by helping to stop cancer cells from growing.

What is the dosage of Regorafenib?

PO- The recommended dose is 160mg, once daily for the first 21 days of each 28-day cycle.

How should Regorafenib be taken?

It comes as a tablet to take by mouth with food.

What are the warnings and precautions for Regorafenib?

• Caution should be exercised in patients with history of bleeding problems, high blood pressure, heart, liver, or kidney diseases, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Avoid drinking grapefruit juice while taking this medication.

• Patient may develop with increased risk of Reversible Posterior Leukoencephalopathy Syndrome (RPLS). If it is so consult with your doctor immediately.

What are the side effects of Regorafenib?

Most Common- Weakness, fatigue, decreased appetite and food intake, Hand-foot skin reaction (HFSR) (palmar-plantar erythrodysesthesia [PPE]), diarrhea, weight loss, and infection.
General - Fever.
Metabolic - Anemia, weight loss.
Skin - Rash.
Gastrointestinal - Diarrhea.
Heart - High blood pressure, bleeding.
Respiratory - Difficulty in breathing.