Romidepsin Medication Information

Discover comprehensive details about Romidepsin, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Romidepsin brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Romidepsin

Pronunciation : ROE-mi-DEP-sin

Brand Names or Trade Names of Romidepsin

International :

Istodax

Why is Romidepsin Prescribed? (Indications)

This medication is a histone deacetylase (HDAC) inhibitor, prescribed for cutaneous T-cell lymphoma (CTCL) or peripheral T-cell lymphoma (PTCL). It works by slowing the growth of cancer cells.

When should Romidepsin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Romidepsin?

IV- The recommended dose is 14 mg/m², over a 4-hour period infusion on days 1, 8 and 15 of a 28-day cycle.

How should Romidepsin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Romidepsin?

• Caution should be exercised in patients with history of liver or kidney impairment, irregular heartbeat or other heart diseases, nausea, vomiting, or diarrhea, who have undergone chemotherapy, any allergy, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• Patient may develop with increased risk of tumor lysis syndrome (TLS) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, nausea, vomiting, diarrhea, or loss of appetite. If it is so consult with your doctor.

• Monitor complete blood cell counts, blood electrolyte levels, and electrocardiograms (ECGs) regularly while taking this medication.

What are the side effects of Romidepsin?

Gastrointestinal - Nausea, vomiting, diarrhea, constipation, abdominal pain, mouth ulcer, indigestion, loss of appetite.
Central Nervous System - Weakness, fatigue, headache.
Metabolic - Decreased weight and fluid retention.
Blood - Anemia, decrease in white blood cells and platelets.
Miscellaneous - Fever, chills, cough, difficulty in breathing, fast heart rate.