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Ruxolitinib - Indications, Dosage, Side Effects and Precautions

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Ruxolitinib Medication Information

Discover comprehensive details about Ruxolitinib, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Ruxolitinib brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Ruxolitinib

Brand Names or Trade Names of Ruxolitinib

International :


Jakafi

Why is Ruxolitinib Prescribed? (Indications)

This medication is a kinase inhibitor, prescribed for high-risk myelofibrosis. It blocks certain substances (JAK1 and JAK2) that are involved in myelofibrosis.

When should Ruxolitinib not be taken? (Contraindications)

Contraindicated in patients with known hypersensitivity.

What is the dosage of Ruxolitinib?

PO- The starting dose is 20 mg 2 times per day, for patients with platelet count greater than 200 X 109/L.

How should Ruxolitinib be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Ruxolitinib?

• Caution should be exercised in patients with history of liver or kidney impairment, patients on dialysis, during pregnancy and breastfeeding.

• It may cause dizziness, avoid performing any hazardous activity while taking this medication.

• Patient may develop with certain types of infection; discuss with your healthcare provider before taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Monitor complete blood count regularly while taking this medication.

What are the side effects of Ruxolitinib?

Most Frequent - Thrombocytopenia and anemia.
Miscellaneous - Bruising, dizziness, headache, urinary tract infection, weight gain, flatulence, herpes zoster.

What are the other precautions for Ruxolitinib?

Avoid excess dosage.

What are the storage conditions for Ruxolitinib?

Store it at room temperature (20° to 25°C).

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