Saxagliptin and Metformin Medication Information

Learn everything you need to know about Saxagliptin and Metformin-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Saxagliptin and Metformin brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Saxagliptin and Metformin

Pronunciation : SAX-a-GLIP-tin- met-FOR-min

Brand Names or Trade Names of Saxagliptin and Metformin

International :

Kombiglyze XR

Why is Saxagliptin and Metformin Prescribed? (Indications)

This combination medication contains two oral antihyperglycemic medications (a dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide), prescribed for type 2 diabetes. It is not for treating type 1 diabetes. It works by decreasing glucose (sugar) production in the liver and by regulating the levels of insulin.

When should Saxagliptin and Metformin not be taken? (Contraindications)

Contraindicated in patients with metabolic acidosis, diabetic ketoacidosis, severe kidney impairment, and hypersensitivity.

What is the dosage of Saxagliptin and Metformin?

PO- The recommended initial dose is (metformin-saxagliptin 500 mg-5 mg) 1 tablet once daily.

How should Saxagliptin and Metformin be taken?

It comes as a tablet to take by mouth, with the evening meal.

What are the warnings and precautions for Saxagliptin and Metformin?

• Caution should be exercised in patients with history of heart problems, lung, thyroid, and/or stomach problems, hormone problems, lactic acidosis, gallstones, high blood cholesterol, alcohol abuse, had recent surgery, angioedema, who are taking other medications, any allergy, elderly, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Follow the diet and exercise program as directed by your physician.

• It may lead to dehydration so drink plenty of fluid.

• Monitor kidney function, fasting blood glucose, hemoglobin A1c, and complete blood cell counts regularly while taking this medication.

What are the side effects of Saxagliptin and Metformin?

Most Common - Upper respiratory tract infection, urinary tract infection, headache.
Miscellaneous - Sinusitis, abdominal pain, gastroenteritis, and vomiting.