Sodium Nitroprusside Medication Information

Discover comprehensive details about Sodium Nitroprusside, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Sodium Nitroprusside brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Sodium Nitroprusside

Pronunciation : nye-troe-PRUSS-ide SO-dee-uhm

ICD Code : Y52.5 Therapeutic Classification : Anti- Hypertensives

Brand Names or Trade Names of Sodium Nitroprusside

India :

Niside | Nipress | Sonide

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International :

Nitropress, Nipride

Why is Sodium Nitroprusside Prescribed? (Indications)

This medication is a potent vasodilator, prescribed for controlling low blood pressure in order to reduce bleeding during surgery. It is also used for high blood pressure.

When should Sodium Nitroprusside not be taken? (Contraindications)

Contraindicated in patients with compensatory hypertension, patients with known inadequate cerebral circulation, congenital (Leber's) optic atrophy or with tobacco amblyopia, congestive heart failure, and hypersensitivity.

What is the dosage of Sodium Nitroprusside?

Adult: IV- Hypertensive crisis- For patients not receiving any antihypertensives: Initial: 0.3-1.5 mcg/kg/min, adjust gradually if needed.
Induction of hypotension during anesthesia- Recommended maximum dose is 1.5 mcg/kg/min.

How should Sodium Nitroprusside be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Sodium Nitroprusside?

• Caution should be exercised in patients with under active thyroid, kidney or liver impairment, heart disease, stroke, elderly, lung disease, anemia, dehydration, absence of urination, during pregnancy and breastfeeding.

• Monitor acid-based metabolic problems and avoid excess dosage in order to minimize cyanide accumulation.

• Avoid abrupt withdrawal.

What are the side effects of Sodium Nitroprusside?

Serious Effects - Thiocyanate toxicity, cyanide toxicity and increased intracranial pressure.
Most Common - Abdominal pain, apprehension, diaphoresis, dizziness, headache, muscle twitching, nausea, palpitations, restlessness and retching.
Heart - Slow or fast heart rate and electrocardiographic changes.
Skin - Rash.
Metabolic - Underactive thyroid.
Gastrointestinal - Ileus.
Blood - Decreased platelet aggregation.
Central Nervous System - Stroke.
Miscellaneous - Flushing, venous streaking, irritation at the infusion site.