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Sodium Polystyrene Sulfonate - Indications, Dosage, Side Effects and Precautions

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Sodium Polystyrene Sulfonate Medication Information

Learn everything you need to know about Sodium Polystyrene Sulfonate-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Sodium Polystyrene Sulfonate brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Sodium Polystyrene Sulfonate
Pronunciation : SOE-dee-um POL-ee-STYE-reen SUL-foe-nate
Therapeutic Classification : Potassium-removing Resin

Brand Names or Trade Names of Sodium Polystyrene Sulfonate

International :


Kayexalate, Kionex, SPS

Other Name(s) of Sodium Polystyrene Sulfonate


Potassium removal Polysterene Sulphonate Resin.

Why is Sodium Polystyrene Sulfonate Prescribed? (Indications)

This medication is a potassium-removing resin, prescribed for hyperkalemia (without ECG changes).  It affects the exchange of sodium and potassium in the body.

When should Sodium Polystyrene Sulfonate not be taken? (Contraindications)

Contraindicated in patients with obstructive bowel disease, and hypersensitivity.

What is the dosage of Sodium Polystyrene Sulfonate?

Dosage: Adults: PO- The recommended dose is 15 g, 3-4 times daily in water. Children: 0.5- 1 g/kg daily in divided doses.

How should Sodium Polystyrene Sulfonate be taken?

It comes as a powder to take by mouth, with water.

What are the warnings and precautions for Sodium Polystyrene Sulfonate?

• Caution should be exercised in patients with history of heart or kidney disease, high blood pressure, constipation, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• Monitor blood potassium and other blood electrolyte levels, and electrocardiograms (ECGs) regularly while taking this medication.

What are the side effects of Sodium Polystyrene Sulfonate?

Gastrointestinal - Rectal ulceration, GI irritation, anorexia, nausea, vomiting, constipation and diarrhea.

What are the other precautions for Sodium Polystyrene Sulfonate?

Avoid excess dosage.

What are the storage conditions for Sodium Polystyrene Sulfonate?

Store in a dry place below 30°C.
Suspensions of the resin should be freshly prepared and not to be stored beyond 24 hours.

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