Sorafenib Medication Information

Get detailed information on Sorafenib, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Sorafenib provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Sorafenib

Pronunciation : soe-RAF-e-nib

Trade Names/Brand Names of Sorafenib

International :

Nexavar

Why is Sorafenib Prescribed? (Indications)

This medication is a kinase inhibitor, prescribed for renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer). It decreases tumor growth and replication.

When should Sorafenib not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Sorafenib?

Adult- PO- The recommended dose is 400 mg (two 200 mg tablets) twice daily.

How should Sorafenib be taken?

It comes as a tablet to take by mouth, two times per day on an empty stomach.

What are the warnings and precautions for Sorafenib?

• Patient may develop heart attack, bleeding, hypertension, gastrointestinal perforation.

Caution needed for patients with history of high blood pressure, bleeding problems, chest pain, a heart attack, kidney disease other than kidney cancer, or heart or liver disease.

• It could cause birth defects, hence both males and females are advised to use contraception while on this medication.

It may reduce the number of clot-forming cells (platelets), avoid situations in which bruising or injury may occur.

What are the side effects of Sorafenib?

Heart- High blood pressure, reduced blood supply to the heart, heart attack.
Central Nervous System- Fatigue, sensory nerve disease, weakness, headache, depression.
Skin- Hair loss, skin disease, rashes, itching, redness, allergy.
Gastrointestinal- Abdominal pain, diarrhea, loss of appetite, nausea, vomiting, constipation, stomach upset, difficulty in swallowing, mouth ulcer, gastrointestinal perforation.
Genitourinary- Impotence, kidney failure.
Blood-Lymphatic- Anemia, decrease in platelets, white blood cells, bleeding.
Liver- Liver dysfunction.
Metabolic- Weight loss.
Musculoskeletal- Joint and/ or muscle pain.
Respiratory- Difficulty in breathing, hoarseness.
Miscellaneous- Severe allergic reaction, influenza-like illness, fever.