- Tacrine - (https://www.ncbi.nlm.nih.gov/books/NBK547868/ )
- Tacrine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease - (https://pubmed.ncbi.nlm.nih.gov/7521234/ )
- Tacrine - (https://pubchem.ncbi.nlm.nih.gov/compound/Tacrine#section=Exposure-Routes )
- Tacrine: first drug approved for Alzheimer's disease - (https://pubmed.ncbi.nlm.nih.gov/7919566/)
Tacrine Medication Information
Get detailed information on Tacrine, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The updated prescription information on Tacrine provides an overview of possible side effects, precautions, warnings, and storage tips.
You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.
Generic Name : Tacrine Pronunciation : tak-reen ICD Code : Y51.8 Therapeutic Classification : Anti- Alzheimer's AgentsTrade Names/Brand Names of Tacrine
International :
Cognex
Why is Tacrine Prescribed? (Indications)
This medication is a cholinesterase inhibitor, prescribed for mild to moderate dementia. It increases the amount of acetylcholine in the brain.When should Tacrine not be taken? (Contraindications)
Contraindicated in patients previously treated with this medication, who have too much bilirubin in blood, and hypersensitivity.What is the dosage of Tacrine?
Adults—Initial- 10 milligrams (mg) four times a day. Maximum: 40 mg four times a day.How should Tacrine be taken?
It comes as a capsule to take by mouth, on an empty stomach.What are the warnings and precautions for Tacrine?
• Caution should be exercised in patients with history of ulcers, seizures, problems with urinary system, asthma, blood vessel problems, heart, kidney, liver, lung or stomach disorders.• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
• Avoid alcohol consumption.
What are the side effects of Tacrine?
Most Common- Increase in liver test called alanine aminotransferase (ALT), nausea, vomiting, diarrhea, indigestion, muscle pain, loss of appetite and unsteadiness.Body As A Whole - Headache, fatigue, chest pain, decrease in weight, back pain and weakness.
Gastrointestinal - Loss of appetite, abdominal pain, flatulence and constipation.
Blood - Bruising.
Musculoskeletal- Muscle pain.
Central Nervous System- Dizziness, confusion, unsteadiness, sleeplessness, drowsiness, tremor, agitation, depression, abnormal thinking, anxiety and hallucinations.
Respiratory - Nose inflammation, upper respiratory infection and coughing.
Skin- Rash, facial flushing and skin flushing.
Genitourinary- Urination frequency, urinary tract infection and urinary incontinence.