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Thiopental - Indications, Dosage, Side Effects and Precautions

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Thiopental Medication Information

Discover comprehensive details about Thiopental, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Thiopental brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Thiopental
Pronunciation : thye-oh-PEN-tol
ICD Code : Y48.2 Therapeutic Classification : General Anesthetics

Brand Names or Trade Names of Thiopental

India :

International :


Pentothal.

Why is Thiopental Prescribed? (Indications)

This medication is a barbiturate general anesthetic, prescribed for induction of anesthesia. It depresses the central nervous system, causing mild sleep.

When should Thiopental not be taken? (Contraindications)

Contraindicated in patients with severe heart disease, shock, absence of suitable vein for administration, blood disease porphyria and hypersensitivity.

What is the dosage of Thiopental?

Test Dose: It is advisable to inject a small dose of 25 to 75 mg (1 to 3 mL of a 2.5% solution)
Adult: IV- Induction of anesthesia as 2.5 or 5% solution: 100-150 mg, repeat every 30-60 sec if needed. Max: 500 mg. Max in pregnant women: 250 mg.
Status epilepticus with assisted ventilation: As 2.5% solution: 75-125 mg.
Reduction of raised intracranial pressure intermittent bolus injection of 1.5-3.5 mg/kg, if adequate ventilation is provided.

How should Thiopental be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Thiopental?

• Caution should be exercised in patients with history of kidney or liver problems, lung or respiratory tract diseases, heart problems, low blood pressure, addison disease, asthma, myasthenia gravis, thyroid problems, or increased pressure in the brain, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness or lightheadedness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption during the treatment.

What are the side effects of Thiopental?

Most Common- Respiratory depression, heart attack, irregular heart rate, drowsiness, sneezing, coughing, asthma and shivering.
Allergic Reactions- Hives, itching and swelling.

What are the other precautions for Thiopental?

Avoid excess dosage.

What are the storage conditions for Thiopental?

Store it at controlled room temperature (15° to 30°C), and in an airtight container.

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