Thiotepa Medication Information

Learn everything you need to know about Thiotepa-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Thiotepa brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Thiotepa

Pronunciation : (thye oh tep' a)

Brand Names or Trade Names of Thiotepa

Tespamin

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International :

Thioplex

Why is Thiotepa Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for ovary or breast cancer. It works by killing cancer cells.

When should Thiotepa not be taken? (Contraindications)

Contraindicated in patients with liver, kidney disease, bone marrow depression and hypersensitivity.

What is the dosage of Thiotepa?

Breast and Ovarian Carcinoma: Adults- IV- 0.3 to 0.4 mg/kg every 1 to 4 week. Alternative regimens- 0.2 mg/kg/day for 4 to 5 days every 2 to 4 week; or 6 mg/m 2 /day for 4 to 5 days every 2 to 4 week.

How should Thiotepa be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Thiotepa?

• Caution should be exercised in patients with history of kidney or liver problems, bone marrow problems, agranulocytosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts, avoid injury or bruising.

• Avoid live vaccination.

What are the side effects of Thiotepa?

General - Fatigue and weakness.
Hypersensitivity - Allergic reactions - rash, hives, laryngeal edema, asthma, shock and wheezing.
Local - Skin inflammation and pain at the injection site.
Gastrointestinal - Nausea, vomiting, abdominal pain and loss of appetite.
Genitourinary - Painful urination and urinary retention.
Respiratory - Difficulty in breathing.
Central Nervous System - Dizziness, headache and blurred vision.
Skin - Hair loss.
Eye - Eye inflammation.
Genitourinary - Absence of menstrual periods and decrease in sperm count.