Information about Tipranavir

Generic Name : Tipranavir
Up-to-date prescription details regarding Tipranavir are provided here.

Pronunciation : tye-PRAN-a-vir

Learn the correct pronunciation of the Tipranavir, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y41.5 Therapeutic Classification : Antivirals

Trade Names/Brand Names of Tipranavir

International :

Aptivus

Why is Tipranavir Prescribed? (Indications)

This medication is a protease inhibitor, prescribed for HIV/AIDS with ritonavir. It works by decreasing the amount of HIV in the blood.

When should Tipranavir not be taken? (Contraindications)

Contraindicated in patients with moderate or severe liver impairment, who are taking antiarrhythmics, antimycobacterials, ergot derivatives, GI motility agent, herbal products, HMG CoA reductase inhibitors, neuroleptic, PDE-5 inhibitors, sedatives/hypnotics and hypersensitivity.

What is the dosage of Tipranavir?

Adults- The recommended adult dose is 500 mg (two 250 mg capsules or 5 mL oral solution) co-administered with 200 mg of ritonavir, twice daily.
Pediatric Patients (age 2 to 18 years)- The recommended dose is 14 mg/kg with 6 mg/kg ritonavir twice daily. Maximum dose is 500 mg co-administered with ritonavir 200 mg twice daily.

How should Tipranavir be taken?

It comes as a capsule and an oral solution (liquid) to take by mouth, with or without food.

What are the warnings and precautions for Tipranavir?

• Caution should be exercised in patients with cholesterol or lipid problems, diabetes, sugar, liver or kidney problems, bleeding problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• It may increase/decrease body fat in different areas of body such as back of your neck and upper shoulders, if you notice any of these changes consult with your doctor.

• Avoid exposure to sunlight.

• It may decrease the effectiveness of hormonal contraceptives, use different contraceptive method.

Avoid sexual intercourse; sharing of needles, injection supplies or items like toothbrushes or razors while taking this medication in order to prevent spread of HIV infection.

What are the side effects of Tipranavir?

Most frequent- Diarrhea, nausea, vomiting, fever, fatigue, headache and abdominal pain.
Blood - Anemia and decrease in white blood cells and platelets.
Gastrointestinal - Indigestion, flatulence, gastro esophageal reflux disease and inflammation of pancreas.
General Disorders - Influenza-like illness, uneasiness and hypersensitivity
Metabolic- Increase in fat, dehydration, decreased weight, increase in liver enzymes, decreased appetite and diabetes mellitus.
Musculoskeletal- Muscle pain and muscle cramps.
Central Nervous System - Sleeplessness, nerve damage, dizziness, stroke and drowsiness.
Respiratory- Difficulty in breathing.
Skin- Rash and itching.
Liver- Liver failure/inflammation.

What are the other precautions for Tipranavir?

It may increase blood sugar with symptoms of drowsiness or excessive thirst, if it so consult with your doctor.
Monitor viral load, CD4 count, triglyceride and lipid levels and liver functions while taking this medication.