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Tolbutamide - Indications, Dosage, Side Effects and Precautions

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Tolbutamide Medication Information

Learn everything you need to know about Tolbutamide-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Tolbutamide brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Tolbutamide
Pronunciation : tole byoo' ta mide
ICD Code : Y42.3 Therapeutic Classification : Antidiabetics

Brand Names or Trade Names of Tolbutamide

India :

International :


Diabinese, Orinase, Tolinase, Apo-Tolbutamide, Artosin, Diaval, Mobenol, Novo-Butamide, Rastinon

Why is Tolbutamide Prescribed? (Indications)

This medication is an antidiabetic agent, prescribed for type 2 diabetes. It is used along with diet and exercise. It causes the pancreas to release insulin.

When should Tolbutamide not be taken? (Contraindications)

Contraindicated in patients with diabetes, severe burn and hypersensitivity.

What is the dosage of Tolbutamide?

PO- The recommended dose range is 0.5 to 3 grams daily.

How should Tolbutamide be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Tolbutamide?

• Caution should be exercised in patients with history of liver, kidney, thyroid, or heart problems, stomach problem, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, blurred vision, or lightheadedness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• It may affect blood sugar level; monitor sugar level regularly.

• Avoid exposure to sunlight.

• It should not be used in children.

What are the side effects of Tolbutamide?

Most Common - Feeling of stomach fullness, heartburn, nausea and decrease in blood sugar level.
Gastrointestinal - Jaundice, nausea and heartburn.
Skin - Allergic skin reactions such as itching, redness, hives, sensitivity to light and bruising.
Blood - Decrease in white/red blood cells, platelets and anemia.
Miscellaneous - Weakness, fatigue, dizziness, vertigo, malaise and headache are reported very rarely.

What are the other precautions for Tolbutamide?

Avoid excess dosage.

What are the storage conditions for Tolbutamide?

Store it at room temperature.

Schedule : G
Drugs that are to be used only under medical supervision.

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