Tolcapone Medication Information

Discover comprehensive details about Tolcapone, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Tolcapone brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Tolcapone

Pronunciation : TOLE-ka-pone

ICD Code : Y46.7 Therapeutic Classification : Antiparkinson Agents

Brand Names or Trade Names of Tolcapone

International :

Tasmar

Why is Tolcapone Prescribed? (Indications)

This medication is a catechol-O-methyl transferase (COMT) inhibitor, prescribed for Parkinson's disease along with levodopa/carbidopa. It prolongs the anti-Parkinson's effect of levodopa.

When should Tolcapone not be taken? (Contraindications)

Contraindicated in patients with rhabdomyolysis (condition in which skeletal muscle cells break down), liver disease and hypersensitivity.

What is the dosage of Tolcapone?

Initial: The recommended dose is 100 mg, three times per day.

How should Tolcapone be taken?

It comes as a tablet to take by mouth, as directed by your physician.

What are the warnings and precautions for Tolcapone?

• Caution should be exercised in patients with history of heart or kidney disease, elderly, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Tolcapone?

Most Common- Movement disorder, nausea, sleep disorder, involuntary movements, excessive dreaming, loss of appetite, muscular cramps, orthostatic complaints, drowsiness, diarrhea, confusion, dizziness, headache, hallucinations, vomiting, constipation, fatigue, upper respiratory tract infection, falling, increased sweating, urinary tract infection, dry mouth, abdominal pain and urine discoloration.
Central Nervous System- Depression, sensory loss, tremor, speech disorder, unsteadiness and emotional lability.
Gastrointestinal- Tooth disorder.
Body as a Whole- Flank pain, accidental injury, abdominal pain and infection.
Heart- Palpitations.
Musculoskeletal- Muscle pain.
Genitourinary- Urinary incontinence and impotence.
Respiratory- Inflammation of bronchus and pharynx.
Eye and ENT- Ringing in the ear.