Tolvaptan Medication Information

Discover comprehensive details about Tolvaptan, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Tolvaptan brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Tolvaptan

Pronunciation : tol-VAP-tan

Brand Names or Trade Names of Tolvaptan

Tolvamac (15mg) | Tolvamac (30mg) | Vaptan

More info >>>

International :

Samsca

Why is Tolvaptan Prescribed? (Indications)

Tolvaptan is a selective vasopressin V2-receptor antagonist, prescribed for hyponatremia (low blood sodium levels).
It works by increasing fluid excretion from the body.

When should Tolvaptan not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Tolvaptan?

PO- The usual starting dose is 15 mg administered once daily. Increase up 30 mg once daily. Maximum: 60 mg once daily.

How should Tolvaptan be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Tolvaptan?

• Cautions should be exercised in patients with history of diabetes, kidney disease, liver disease, use/abuse of alcohol, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• Avoid becoming dehydrated; drink adequate fluids.

• It may raise blood sugar level; if it is so consult with your doctor.

♦Patient may develop with increased risk of Osmotic demyelination syndrome.

What are the side effects of Tolvaptan?

Most Common - Increased thirst, dry mouth, weakness, constipation, increased urination and increased blood sugar.
Blood - Blood clot events.
Heart - Severely abnormal heart rhythm, prolonged prothrombin time.
Gastrointestinal - Intestinal inflammation.
Metabolic - Diabetic ketoacidosis.
Musculoskeletal - Rhabdomyolysis.
Central Nervous System - Stroke.
Genitourinary - Urethral bleeding, vaginal bleeding.
Respiratory - Blood clot in lungs, respiratory failure.
Vascular disorder - Deep vein thrombosis.