Tositumomab Medication Information

Discover comprehensive details about Tositumomab, including its pronunciation, uses, dosage instructions, indications, and guidelines on how and when to take it or avoid it.

The updated prescription information covers potential side effects, precautions, warnings, and storage recommendations.

Additionally, explore the Tositumomab brands available in India and internationally, along with pricing information. For personalized advice, consult your healthcare provider.

Generic Name : Tositumomab

Pronunciation : tos-IT-too-moe-mab

Therapeutic Classification : Radioactive Monoclonal Antibody

Brand Names or Trade Names of Tositumomab

International :

Bexxar

Why is Tositumomab Prescribed? (Indications)

This medication is a radioactive monoclonal antibody, prescribed for non-Hodgkin’s lymphoma in patients who have not responded to other therapy. It works by killing cancer cells.

When should Tositumomab not be taken? (Contraindications)

Contraindicated in pregnant women, and patients with known hypersensitivity.

What is the dosage of Tositumomab?

IV- The recommended dose is 5.0 mCi Iodine-131 and 35 mg Tositumomab in 30 ml 0.9% sodium chloride over 20 minutes.

How should Tositumomab be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Tositumomab?

• Caution should be exercised in patients with history of infection, thyroid problems, kidney impairment, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid vaccination during the treatment period.

• Patient may develop with increased risk of thyroid damage; consult with your doctor before taking this medication.

• It may reduce blood cells, which may increase the risk of bleeding or infection. Avoid bruising or injury and contact with people who have infections.

What are the side effects of Tositumomab?

Most Common - Decrease in blood cells.
Body as a Whole - Weakness, fever, infection, body pain, chills, headache, abdominal pain, back pain, chest pain, and neck pain.
Heart - Low blood pressure and dilatation of blood vessels.
Gastrointestinal - Nausea, vomiting, loss of appetite, diarrhea, constipation, and indigestion.
Endocrine - Decrease in thyroid hormone.
Metabolic - Swelling in the extremities, and weight loss.
Musculoskeletal - Joint pain and muscle pain.
Central Nervous System - Dizziness, and drowsiness.
Respiratory - Increased cough, difficulty in breathing, nose inflammation and lung infection.
Skin - Rash, itching, and increased sweating.