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Zileuton - Indications, Dosage, Side Effects and Precautions

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Zileuton Medication Information

Get detailed information on Zileuton, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Zileuton provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Zileuton
Pronunciation : zye-LOO-ton
ICD Code : Y45.9 Therapeutic Classification : Anti- Inflammatory Agents

Trade Names/Brand Names of Zileuton

International :


Zyflo, Zyflo Cr

Why is Zileuton Prescribed? (Indications)

This medication is a leukotriene synthesis inhibitor, prescribed for asthma. It blocks the formation of a substance called leukotriene that helps to remove asthma and allergic symptoms.

When should Zileuton not be taken? (Contraindications)

Contraindicated in patients with liver disease and hypersensitivity.

What is the dosage of Zileuton?

PO- The recommended dose is 1200mg two times per day.

How should Zileuton be taken?

It comes as a tablet to take by mouth, within one hour after the morning and evening meals.

What are the warnings and precautions for Zileuton?

• Caution should be exercised in patients with history of mental illness, liver impairment, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• Avoid alcohol consumption while taking this medication.

• Patient may develop with mental or mood changes or suicidal thoughts; watch them carefully.

• Continue the use of inhalers if you have used it before the treatment.

• Monitor liver functions regularly while taking this medication.

It should not be used in children less than 12 years old.

What are the side effects of Zileuton?

Most Common- Inflammation of sinus, nausea and throat pain.
Gastrointestinal- Abdominal pain, diarrhea, indigestion and vomiting.
Miscellaneous- Rash, severe allergic reactions and liver damage.

What are the other precautions for Zileuton?

Monitor liver functions regularly while taking this medication.

What are the storage conditions for Zileuton?

Store it at controlled room temperature (20 and 25°C) and in an airtight container. Keep away from children.

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