Fluoroquinolones - A Review II

(Compiled by T R Ramanujam)
Prof Head, Department of pharmacology

Adverse effects

Drug Interactions

Pharmacological outline of Sparfloxacin

FUTURE DEVELOPMENTS of Quinolones

Drug Interactions

Drug Interactions:

Primary drug- Quinolones. Interact with

X Warfarin = enhanced anticoagulation

X H2 Antagonists = quinolone absorption

X Cyclosporin = toxicity

X = decreases serum concentration of quinolone

X NSAIDs = Convulsions

X Insulin & oral hypoglycemics = hypoglycemia.