Are you taking Acetaminophen? Are you aware of the dangers of combining Acetaminophen with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers
Go to source).
Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults
Go to source).
References
Acetaminophen Interactions with Food and Herbs
Watercress: The levels of acetaminophen's oxidative metabolites decrease when watercress and acetaminophen are taken together. This may be due to the inhibition of the drug's oxidative metabolism(1✔ ✔Trusted SourceDecrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers
Go to source).
Acetaminophen Interactions with Alcohol
Avoid drinking alcohol while taking acetaminophen because it may raise the risk of hepatotoxicity(2✔ ✔Trusted SourceEthanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults
Go to source).
When and How to Take Acetaminophen
- Acetaminophen is available as a tablet, chewable tablet, capsule, suspension or solution, extended-release tablet, and orally disintegrating tablet to be taken orally, with or without food.
- Avoid excess dosage.
- Do not crush or chew extended-release tablets, because it can release the entire drug at once, increasing the risk of side effects.
- Stop taking acetaminophen and contact your doctor if your symptoms worsen or when you develop new or unexpected symptoms.(3✔ ✔Trusted Source
Acetaminophen: MedlinePlus Drug Information
Go to source).
References
- Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers (https://pubmed.ncbi.nlm.nih.gov/8988067/)
- Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults (https://pubmed.ncbi.nlm.nih.gov/10872641/)
- Acetaminophen: MedlinePlus Drug Information (https://medlineplus.gov/druginfo/meds/a681004.html)
