Are you taking Bendamustine ? Are you aware of the dangers of combining Bendamustine with certain foods, herbs or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Malaker Ed (2022). Caffeine Drug Interactions You Need to Know.
Go to source).
References
1. Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet 1999;36:425-438. doi: 10.2165/00003088-199936060-00004
2. Malaker Ed (2022). Caffeine Drug Interactions You Need to Know. https://coffeeaffection.com/caffeine-drug-interactions/
3. iwfm.com (2021) Bendamustine Fact Sheet. https://iwmf.com/wp-content/uploads/2020/10/Bendamustine-Fact-Sheet-English.pdf
4. National Library of Medicine: Bendamustine MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a608034.html
Bendamustine Interactions with Food and Herbs
Tobacco:- Using tobacco products may cause CYP1A2 metabolism and decrease Bendamustine exposure resulting in reduced efficacy.
- It is best to avoid tobacco when you are on Bendamustine (1✔ ✔Trusted Source
1.Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet. 1999;36:425-438. doi: 10.2165/00003088-199936060-00004
Go to source).
Bendamustine Interactions with Alcohol
- Drinking a small amount of alcohol does not affect the efficacy of Bendamustine.
- It may cause infertility in men (3✔ ✔Trusted Source
iwfm.com (2021) Bendamustine Fact Sheet
Go to source).
Bendamustine Interactions with Caffeine
When caffeine is used along with Bendamustine, the amount of the medication in the blood may increase which has an impact on bone marrow function (2✔ ✔Trusted SourceMalaker Ed (2022). Caffeine Drug Interactions You Need to Know.
Go to source).
When and How to Take Bendamustine
- Bendamustine is available as a solution or as a powder that must be mixed with liquid and injected intravenously (into a vein) over 10 minutes or infused over 30 or 60 minutes by a healthcare provider.
- Patients will be given Bendamustine for 2 days during each of your prescribed treatment cycles. (For CLL, each treatment cycle lasts 28 days. For NHL, each treatment cycle lasts 21 days).
- Bendamustine may be given with other medications to prevent certain of its side effects.
- Bendamustine dosage and schedule will be determined by your doctor depending on several criteria including your height, weight, blood count and any other medical conditions.
- If you experience discomfort, irritation, redness, or swelling at the injection site contact your doctor.
- Your doctor may also give you other medications to prevent certain side effects (4✔ ✔Trusted Source
National Library of Medicine: Bendamustine MedlinePlus Drug Information.
Go to source).
References
1. Zevin S, Benowitz NL. Drug interactions with tobacco smoking. Clin Pharmacokinet 1999;36:425-438. doi: 10.2165/00003088-199936060-00004
2. Malaker Ed (2022). Caffeine Drug Interactions You Need to Know. https://coffeeaffection.com/caffeine-drug-interactions/
3. iwfm.com (2021) Bendamustine Fact Sheet. https://iwmf.com/wp-content/uploads/2020/10/Bendamustine-Fact-Sheet-English.pdf
4. National Library of Medicine: Bendamustine MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a608034.html