Are you taking Ceritinib? Are you aware of the dangers of combining Ceritinib with certain foods and herbs? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Tobacco: Using tobacco products such as cigarettes while taking ceritinib can raise nicotine levels in the blood and causes side effects (1✔ ✔Trusted Source
FDA Approved Drug Products: Zykadia Ceritinib Oral Capsules.
Go to source).
St John's Wort: Avoid St. John's Wort that induces the CYP3A metabolism of ceritinib and may reduce its serum concentration (2✔ ✔Trusted Source
DrugBank Online. Ceritinib: Uses, Interactions, Mechanism of Action.
Go to source).
References
1. FDA Approved Drug Products: Zykadia Ceritinib Oral Capsules. Retrieved on 8th June 2022 from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205755s009lbl.pdf
2. DrugBank Online. Ceritinib: Uses, Interactions, Mechanism of Action. Retrieved on 9th June 2022 from: https://go.drugbank.com/drugs/DB09063
3. National Library of Medicine. Ceritinib: MedlinePlus Drug Information. Retrieved on 9th June 2022 from: https://medlineplus.gov/druginfo/meds/a614027.html
Ceritinib Interactions with Food and Herbs
Grapefruit:- Interaction of grapefruit juice with ceritinib inhibits CYP3A and cause severe side effects.
- It is better to avoid grapefruit juice with ceritinib (1✔ ✔Trusted Source
FDA Approved Drug Products: Zykadia Ceritinib Oral Capsules.
Go to source).
Tobacco: Using tobacco products such as cigarettes while taking ceritinib can raise nicotine levels in the blood and causes side effects (1✔ ✔Trusted Source
FDA Approved Drug Products: Zykadia Ceritinib Oral Capsules.
Go to source).
St John's Wort: Avoid St. John's Wort that induces the CYP3A metabolism of ceritinib and may reduce its serum concentration (2✔ ✔Trusted Source
DrugBank Online. Ceritinib: Uses, Interactions, Mechanism of Action.
Go to source).
When and How to Take Ceritinib
- Ceritinib is available only on prescription. It comes in the form of a capsule and a tablet to take orally (by mouth).
- Generally it is prescribed to take once a day with food.
- Take the medication at around the same time every day for better results.
- Don't exceed or skip the dose. Even if you miss it, take the medication as soon as you remember.
- Do not double the dose at a time to compensate for the missed dose (3✔ ✔Trusted Source
National Library of Medicine. Ceritinib: MedlinePlus Drug Information.
Go to source).
References
1. FDA Approved Drug Products: Zykadia Ceritinib Oral Capsules. Retrieved on 8th June 2022 from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205755s009lbl.pdf
2. DrugBank Online. Ceritinib: Uses, Interactions, Mechanism of Action. Retrieved on 9th June 2022 from: https://go.drugbank.com/drugs/DB09063
3. National Library of Medicine. Ceritinib: MedlinePlus Drug Information. Retrieved on 9th June 2022 from: https://medlineplus.gov/druginfo/meds/a614027.html
