Are you taking Cyclosporine? Are you aware of the dangers of combining Cyclosporine with certain foods and herbs? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Food-Drug interactions
Go to source).
Pomelo juice: Avoid taking pomelo juice with Cyclosporine as it may result in an increased risk of cyclosporine toxicity such as renal dysfunction, cholestasis, and paresthesias (2✔ ✔Trusted Source
Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans
Go to source).
References
1.Food-Drug interactions
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191675/
2.Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans
https://pubmed.ncbi.nlm.nih.gov/16513449/
3.Cyclosporine: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a601207.html
Cyclosporine Interactions with Food and Herbs
Grapefruit juice: Drinking grapefruit juice with Cyclosporine may result in an increased risk of cyclosporine absorption in the body and cause side effects such as high blood pressure, and kidney damage (1✔ ✔Trusted SourceFood-Drug interactions
Go to source).
Pomelo juice: Avoid taking pomelo juice with Cyclosporine as it may result in an increased risk of cyclosporine toxicity such as renal dysfunction, cholestasis, and paresthesias (2✔ ✔Trusted Source
Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans
Go to source).
When and How to Take Cyclosporine
- Cyclosporine is available in the form of capsule, oral solution.
- It is usually taken once or twice in a day.
- Take Cyclosporine around the same time every day.
- Follow the directions on the prescription carefully.
- Do not take more or less than the prescribed dose.
- Do not discontinue the drug without consulting the physician.
- The unusual smell while opening the cyclosporine capsule package is normal.
- Cyclosporine oral solution may become lumpy if it is exposed to temperatures below 20°C.
- Cyclosporine oral solution can be taken by mixing with orange juice or apple juice but should not be mixed with milk (3✔ ✔Trusted Source
Cyclosporine: Medlineplus Drug Information
Go to source).
References
1.Food-Drug interactions
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191675/
2.Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans
https://pubmed.ncbi.nlm.nih.gov/16513449/
3.Cyclosporine: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a601207.html
