Are you taking Doxycycline? Are you aware of the dangers of combining Doxycycline with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Campbell, N. R., & Hasinoff, B. B. (1991). Iron supplements: a common cause of drug interactions. British journal of clinical pharmacology, 31(3), 251-255. doi: 10.1111/j.1365-2125.1991.tb05525.x
Go to source).
Dairy products: Avoid dairy products such as milk, yogurt, cream and cheese for at least 2 hours before and after taking the medication as it may cause some side effects (2✔ ✔Trusted Source
Kshirsagar N A, Ankalesaria P S. (1987). Effect of food on doxycycline absorption. Journal of Postgraduate Medicine, 33 (3), 117.
Go to source).
References
1. Campbell, N. R., & Hasinoff, B. B. (1991). Iron supplements: a common cause of drug interactions. British journal of clinical pharmacology, 31(3), 251-255. doi: 10.1111/j.1365-2125.1991.tb05525.x
2. Kshirsagar N A, Ankalesaria P S. (1987). Effect of food on doxycycline absorption. Journal of Postgraduate Medicine, 33(3), 117-9.
3. Neuvonen, P. J., Penttila O., Roos, M., & Tirkkonen, J. (1976). Effect of long-term alcohol consumption on the half-life of tetracycline and doxycycline in man. International journal of clinical pharmacology and biopharmacy, 14(4), 303-307. https://pubmed.ncbi.nlm.nih.gov/1002368/
4. PubMed Health (1 July 2016). "Doxycycline (By mouth)". U.S. National Library of Medicine. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0010039/?report=details
Doxycycline Interactions with Food and Herbs
Iron-rich foods: Avoid intake of doxycycline with iron supplements and iron-rich foods like liver, sardines, beef, eggs, kale, tofu, broccoli and spinach as it can affect the absorption of doxycycline in your body (1✔ ✔Trusted SourceCampbell, N. R., & Hasinoff, B. B. (1991). Iron supplements: a common cause of drug interactions. British journal of clinical pharmacology, 31(3), 251-255. doi: 10.1111/j.1365-2125.1991.tb05525.x
Go to source).
Dairy products: Avoid dairy products such as milk, yogurt, cream and cheese for at least 2 hours before and after taking the medication as it may cause some side effects (2✔ ✔Trusted Source
Kshirsagar N A, Ankalesaria P S. (1987). Effect of food on doxycycline absorption. Journal of Postgraduate Medicine, 33 (3), 117.
Go to source).
Doxycycline Interactions with Alcohol
- Do not consume alcohol with doxycycline.
- This can result in a decrease in blood levels of the drug and may affect its efficacy (3✔ ✔Trusted Source
Neuvonen, P. J., Penttila, O., Roos, M., & Tirkkonen, J. (1976). Effect of long-term alcohol consumption on the half-life of tetracycline and doxycycline in man. International journal of clinical pharmacology and biopharmacy, 14(4), 303-307.
Go to source).
When and How to Take Doxycycline
- Doxycycline is available in the form of a capsule, delayed-release capsule, tablet, delayed-release tablet, and suspension (liquid) to be taken orally (by mouth).
- You will usually be advised to take it once or twice a day with a full glass of water on an empty stomach.
- If you have stomach upset while using doxycycline, take it with food or milk.
- Swallow the capsule as a whole instead of crushing, chewing or breaking it. Follow the directions exactly as given on the prescription label.
- Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
- Do not double the dose at a time to compensate for a missed dose (4✔ ✔Trusted Source
PubMed Health (1 July 2016). "Doxycycline (By mouth)". U.S. National Library of Medicine.
Go to source).
References
1. Campbell, N. R., & Hasinoff, B. B. (1991). Iron supplements: a common cause of drug interactions. British journal of clinical pharmacology, 31(3), 251-255. doi: 10.1111/j.1365-2125.1991.tb05525.x
2. Kshirsagar N A, Ankalesaria P S. (1987). Effect of food on doxycycline absorption. Journal of Postgraduate Medicine, 33(3), 117-9.
3. Neuvonen, P. J., Penttila O., Roos, M., & Tirkkonen, J. (1976). Effect of long-term alcohol consumption on the half-life of tetracycline and doxycycline in man. International journal of clinical pharmacology and biopharmacy, 14(4), 303-307. https://pubmed.ncbi.nlm.nih.gov/1002368/
4. PubMed Health (1 July 2016). "Doxycycline (By mouth)". U.S. National Library of Medicine. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0010039/?report=details