Are you taking Isocarboxazid? Are you aware of the dangers of combining Isocarboxazid with certain foods, herbs or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Sub Laban T, Saadabadi A. Monoamine Oxidase Inhibitors (MAOI)
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Cannabis: Avoid using cannabis if you are taking isocarboxazid as it may cause additive CNS depression and other cognitive adverse reactions (2wellrx.com. MARPLAN Lifestyle Interactions.
Go to source).
Sussex Partnership NHS trust Psychotropic Medication and Interaction with Alcohol. (2011)
Go to source).
Go to source).
References
1. Sub Laban T, Saadabadi A. (2022) Monoamine Oxidase Inhibitors (MAOI): https://www.ncbi.nlm.nih.gov/books/NBK539848/
2. wellrx.com. MARPLAN Lifestyle Interactions. https://www.wellrx.com/marplan/lifestyle-interactions/
3. Sussex Partnership NHS trust (2011) Psychotropic Medication and Interaction with Alcohol. http://www.sussexpartnership.nhs.uk/sites/default/files/documents/alcohol_consumption_guidance_on_admin_of_meds_0412_final.pdf
4. National Library of Medicine: Isocarboxazid MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a605036.html#
Isocarboxazid Interactions with Food and Herbs
Tyramine foods: Taking isocarboxazid along with tyramine-containing foods such as cheese, chianti wine, pickled herring, brewer's yeast, fava beans, bananas, and figs can increase the chance of developing a hypertensive crisis (1✔ ✔Trusted SourceSub Laban T, Saadabadi A. Monoamine Oxidase Inhibitors (MAOI)
Go to source).
Cannabis: Avoid using cannabis if you are taking isocarboxazid as it may cause additive CNS depression and other cognitive adverse reactions (2wellrx.com. MARPLAN Lifestyle Interactions.
Go to source).
Isocarboxazid Interactions with Alcohol
When using isocarboxazid, avoid consuming alcohol because it might result in adverse effects such as increased drowsiness, dizziness and an increase in blood pressure (known as a hypertensive crisis) (3✔ ✔Trusted SourceSussex Partnership NHS trust Psychotropic Medication and Interaction with Alcohol. (2011)
Go to source).
Isocarboxazid Interactions with Caffeine
Avoid intake of isocarboxazid along with caffeine-containing products like coffee, tea, cola and chocolate as it can lead to cardiac arrhythmia or severe hypertension (2wellrx.com. MARPLAN Lifestyle Interactions.Go to source).
When and How to Take Isocarboxazid
- Isocarboxazid is available in the form of a tablet to be taken orally (by mouth).
- It is usually taken between two and four times a day with or without food.
- Follow the directions exactly as given on the prescription label.
- If you cannot swallow the tablet, you may crush and mix them with water or juice.
- Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
- Do not double the dose at a time to compensate for a missed dose.
- If you suddenly stop using this medication, you may have withdrawal symptoms such as restlessness, confusion, hallucinations, headache, weakness, and diarrhea.
- Your doctor might gradually reduce your dose to prevent withdrawal symptoms (4✔ ✔Trusted Source
National Library of Medicine: Isocarboxazid MedlinePlus Drug Information.
Go to source).
References
1. Sub Laban T, Saadabadi A. (2022) Monoamine Oxidase Inhibitors (MAOI): https://www.ncbi.nlm.nih.gov/books/NBK539848/
2. wellrx.com. MARPLAN Lifestyle Interactions. https://www.wellrx.com/marplan/lifestyle-interactions/
3. Sussex Partnership NHS trust (2011) Psychotropic Medication and Interaction with Alcohol. http://www.sussexpartnership.nhs.uk/sites/default/files/documents/alcohol_consumption_guidance_on_admin_of_meds_0412_final.pdf
4. National Library of Medicine: Isocarboxazid MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a605036.html#
