Are you taking Loperamide? Are you aware of the dangers of combining Loperamide with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.
Loperamide can kill: A rising trend amidst the opioid epidemic
Go to source).
Valerian: Concurrent use of Valerian and Loperamide may result in delirium with symptoms of confusion, agitation, and disorientation.
St.John’s wort: Taking St. John’s wort and Loperamide together may result in delirium with symptoms of confusion, agitation, and disorientation (2✔ ✔Trusted Source
Herb-drug interactions: Review and assessment of report reliability
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Loperamide: Drug Information
Go to source).
References
1.Loperamide can kill: A rising trend amidst the opioid epidemic
https://journal.chestnet.org/action/showPdf?pii=S0012-3692%2818%2931948-2
2.Herb-drug interactions: Review and assessment of report reliability
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014604/pdf/bcp0052-0587.pdf
3.Loperamide: Drug Information
https://www.nhs.uk/medicines/loperamide/#:~:text=It's%20best%20not%20to%20drink,dizzy%20and%20having%20difficulty%20concentrating.
4.Loperamide: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a682280.html
Loperamide Interactions with Food and Herbs
Grapefruit juice: Avoid taking Grapefruit juice with Loperamide as it may increase the risk of change in heart rhythm or heartbeat (1✔ ✔Trusted SourceLoperamide can kill: A rising trend amidst the opioid epidemic
Go to source).
Valerian: Concurrent use of Valerian and Loperamide may result in delirium with symptoms of confusion, agitation, and disorientation.
St.John’s wort: Taking St. John’s wort and Loperamide together may result in delirium with symptoms of confusion, agitation, and disorientation (2✔ ✔Trusted Source
Herb-drug interactions: Review and assessment of report reliability
Go to source).
Loperamide Interactions with Alcohol
Drinking alcohol with Loperamide may have side effects like feeling sleepy or dizzy and having difficulty in concentrating (3✔ ✔Trusted SourceLoperamide: Drug Information
Go to source).
When and How to Take Loperamide
- Loperamide is available in the form of a tablet, capsule, suspension or oral solution.
- Non-prescription loperamide is taken immediately after each loose bowel movement but not for more than 24-hours.
- Prescription Loperamide can be taken one or more times in a day.
- Take Loperamide with a glass full of water.
- Paediatric dose is different from adult dose.
- Loperamide should not be given to children less than 2 years old.
- When taking loperamide liquid solution, you should use a measuring cup instead of spoons (4✔ ✔Trusted Source
Loperamide: Medlineplus Drug Information
Go to source).
References
1.Loperamide can kill: A rising trend amidst the opioid epidemic
https://journal.chestnet.org/action/showPdf?pii=S0012-3692%2818%2931948-2
2.Herb-drug interactions: Review and assessment of report reliability
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014604/pdf/bcp0052-0587.pdf
3.Loperamide: Drug Information
https://www.nhs.uk/medicines/loperamide/#:~:text=It's%20best%20not%20to%20drink,dizzy%20and%20having%20difficulty%20concentrating.
4.Loperamide: Medlineplus Drug Information
https://medlineplus.gov/druginfo/meds/a682280.html