Food and Herbs Interaction with Saquinavir

Saquinavir Interactions with Food and Herbs

• The interaction of Saquinavir and grapefruit juice increases drug bioavailability, which can lead to serious side effects.
• It is best to avoid grapefruit juice while taking Saquinavir (1^✔ ✔Trusted Source
  Kupferschmidt HH, Fattinger KE, Ha HR, Follath F, Krahenbuhl S. Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man. Br J Clin Pharmacol. 1998 Apr;45(4):355-9. doi: 10.1046/j.1365-2125.1998.t01-1-00687.x. PMID: 9578182; PMCID: PMC1873963.
  
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When and How to Take Saquinavir

• Saquinavir is available in the form of a capsule and a tablet to be taken orally.
• It is usually taken twice a day within 2 hours after a full meal.
• Swallow the tablets as a whole instead of crushing, chewing or breaking them.
• Follow the directions exactly as given on the prescription label.
• Take the medication at the same time every day for better results.
• Do not exceed or skip a dose. If you miss it, take the medication as soon as you remember.
• Do not double the dose at a time to compensate for a missed dose (2^✔ ✔Trusted Source
  National Library of Medicine : Saquinavir MedlinePlus Drug Information.
  
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